Treating Tumors that Move with Respiration

  • Harold C. UrschelJr.
  • John J. Kresl
  • James D. Luketich
  • Lech Papiez
  • Robert D. Timmerman
  • Raymond A. Schulz

Table of contents

  1. Front Matter
    Pages I-XVI
  2. Respiration Motion and Tumor Tracking Techniques

    1. Front Matter
      Pages 1-1
    2. Sohail Sayeh, James Wang, William T. Main, Warren Kilby, Calvin R. Maurer Jr.
      Pages 15-29
    3. Xiaodong Wu, Dongshan Fu, Alberto de la Zerda, Elizabeth Bossart, Hua Shao, Joseph Both et al.
      Pages 31-36
  3. Thoraco-Abdominal Dosimetry, Radiobiology, and Imaging

    1. Front Matter
      Pages 37-37
    2. Alan Alfieri, Jill Rossinow, Madhur Garg, Shalom Kalnicki, Chandan Guha
      Pages 39-53
    3. Medhat M. Osman, Allison Wall, Matthew D. Miller, Nghi Nguyen, Dana A. Oliver, Richard D. Bucholz et al.
      Pages 55-61
    4. Charles L. Lee
      Pages 63-74
    5. Gregory J. Gagnon, Walter Jean, Sonja Dieterich, Huaying Ji, Donald A. McRae
      Pages 75-80
    6. Joost Jan Nuyttens, Jean-Briac Prévost, Mischa S. Hoogeman, Peter C. Levendag
      Pages 81-87
  4. Thoraco-Abdominal Fiducial Placement Strategies

    1. Front Matter
      Pages 89-89
    2. Filip Banovac, Donald McRae, Sonja Dieterich, Kenneth Wong, Lisa Dias, Thomas Chang
      Pages 91-100
    3. James W. Blalock, Clinton A. Medbery III, Astrid E. Morrison, Marianne M. Young, Julie Hensley, Vikki Harriet
      Pages 101-103
    4. Eric D. Anderson, Brian T. Collins, Gregory J. Gagnon, Sean P. Collins, Timothy Mahoney, Filip Banovac et al.
      Pages 105-110
    5. Aline Charabaty-Pishvaian, Richard Desi, Nadim Haddad
      Pages 111-114
  5. Lung Tumor Treatment — Techniques and Experiment

    1. Front Matter
      Pages 115-115
    2. Stuart M. Berman, Mark Huberman, Armin Ernst, David Feller-Kopman, David H. Roberts, Phillip Boiselle et al.
      Pages 133-144
    3. Brian T. Collins, Kelly Erickson, Sean P. Collins, Gregory J. Gagnon, Sonja Dieterich, Donald A. McRae et al.
      Pages 145-153
    4. William T. Brown, Xiaodong Wu, Beatriz E. Amendola, Mark Perman, Fahed Fayad, Silvio García et al.
      Pages 155-163
    5. Neil A. Christie, Steven Burton, Arjun Pennathur, James D. Luketich
      Pages 165-175
    6. Andrew S. Fink, June A. Kim, D. Ross McBride, Micheal J. Hervey II, Penny J. Sinner, Jodi L. Mammenga et al.
      Pages 177-192
  6. Liver and Pancreas Treatment — Techniques and Experiment

    1. Front Matter
      Pages 193-193
    2. Klaus K. Herfarth, Marc W. Münter
      Pages 195-203
    3. Robert M. Goldstein, Brian D. Berger, John K. O’Connor
      Pages 205-215
    4. Scott G. Soltys, Karyn A. Goodman, Albert C. Koong
      Pages 227-239
  7. Emerging Thoraco-Abdominal Radiosurgery Concepts

    1. Front Matter
      Pages 247-247
    2. Jay B. West, Jong Park, John Robinson Dooley, Calvin R. Maurer Jr.
      Pages 249-264
    3. Dongshan Fu, Robert Kahn, Bai Wang, Hongwu Wang, Zhiping Mu, Jong Park et al.
      Pages 265-282
  8. Back Matter
    Pages 295-317

About this book


Stereotactic radiosurgery continues to evolve in ways that allow this powerful technology to reach and treat more tumors in more patients. This volume in the Robotic Radiosurgery series is devoted to theory and practice in the emerging field of stereotactic radiosurgery (also called stereotactic body radiation therapy) for extracranial tumors, particularly those that move as patients breathe.

The book is divided into six sections. The first three sections address tumor motion due to respiration and tumor tracking techniques; dosimetry, radiobiology, and imaging; and fiducial placement systems. The fourth and fifth sections then discuss in depth the use of robotic radiosurgery to treat lung and abdominal tumors, respectively, and a final section explains emerging concepts and techniques. Within this framework, detailed information is provided on the technology and methodology for delivery of high doses of radiation to moving targets, radiobiological and radiological principles, and the challenges faced by clinicians performing extracranial stereotactic radiosurgery. Furthermore, there are thorough reviews of the general clinical literature on stereotactic radiation treatment of tumors of the lungs, liver, and pancreas, and the latest clinical data from clinicians conducting clinical studies using the CyberKnife® Robotic Radiosurgery System.

Special attention is given to the frameless robotic radiosurgery device known as the CyberKnife, the only image-guided radiosurgery system that utilizes intelligent robotics to track, detect, and correct for changes in tumor position during treatments. Tumors that move with respiration are treated with the CyberKnife using a revolutionary new tool, called the Synchrony® Respiratory Tracking System, which can track moving tumors in real-time. This and other features of the CyberKnife are detailed in chapters by CyberKnife users. In addition, researchers in the broader field of stereotactic body radiation therapy were invited to contribute key chapters that place the technical and clinical benefits of CyberKnife into this growing and evolving field.

Efforts have been made to achieve a homogeneous structure throughout the book, and illustrations are of a very high quality. This volume is intended for practitioners and students in all areas of oncology and medicine who are dedicated to the treatment of patients with lesions in the lungs, pancreas, and liver, lesions that move as patients breathe.


Atmen CyberKnife computed tomography (CT) imaging pancreas tumors positron emission tomography radiobiology respiratory system robot robotic radiosurgery stereotactic body radiotherapy surgery tissue tumor tracking ultrasound

Editors and affiliations

  • Harold C. UrschelJr.
    • 1
  • John J. Kresl
    • 2
  • James D. Luketich
    • 3
  • Lech Papiez
    • 4
  • Robert D. Timmerman
    • 4
  • Raymond A. Schulz
  1. 1.Research, Education and Clinical ExcellenceBaylor University Medical CenterDallasUSA
  2. 2.Arizona Oncology Services at St. Joseph’s Hospital & Medical Center Department of Radiation Oncology CyberKnife Center Barrow Neurological InstituteGamma Knife CenterPhoenixUSA
  3. 3.The Heart, Lung and Esophageal Surgery InstituteUniversity of Pittsburgh Medical Center, PUH, C-800PittsburghUSA
  4. 4.Department of Radiation OncologyUniversity of Texas Southwestern Medical CenterDallasUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2007
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-540-69885-2
  • Online ISBN 978-3-540-69886-9
  • Buy this book on publisher's site