Editors:
- Includes supplementary material: sn.pub/extras
Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 191)
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Table of contents (24 chapters)
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Front Matter
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Basic Generators and Effectors
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Pharmacology of cGMP
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Clinical Applications
About this book
After the discovery of endogenous NO formation in the late '80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/sGC interaction and cGMP-dependent signaling. This book is an enthusiastic celebration of cyclic guanosine monophosphate (cGMP) and amply illustrates the importance of this field of science to patients and the way in which the field has evolved. It is exclusively devoted to this exciting and important signaling molecule, addressing all recent advances in understanding guanylate cyclase regulation, NO/sGC interactions, cGMP effector mechanisms and their pathophysiological and pharmacological implications. Particular attention will also be given to clinical applications of the novel cGMP-elevating drugs which are on the horizon, thus spanning the continuum from basic science to clinic.
Editors and Affiliations
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Dept. Pharmacology, Monash University, Clayton, Australia
Harald H. H. W. Schmidt
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Inst. Pharmakologie und Toxikologie, TU München, München, Germany
Franz Hofmann
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Bayer Schering Pharma AG Cardiology Research, Pharma Research Center, Wuppertal, Germany
Johannes-Peter Stasch
Bibliographic Information
Book Title: cGMP: Generators, Effectors and Therapeutic Implications
Editors: Harald H. H. W. Schmidt, Franz Hofmann, Johannes-Peter Stasch
Series Title: Handbook of Experimental Pharmacology
DOI: https://doi.org/10.1007/978-3-540-68964-5
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2009
Hardcover ISBN: 978-3-540-68960-7Published: 09 December 2008
Softcover ISBN: 978-3-642-08848-3Published: 22 November 2010
eBook ISBN: 978-3-540-68964-5Published: 17 December 2008
Series ISSN: 0171-2004
Series E-ISSN: 1865-0325
Edition Number: 1
Number of Pages: XIV, 583
Number of Illustrations: 55 b/w illustrations, 6 illustrations in colour
Topics: Biochemistry, general, Pharmacology/Toxicology, Medical Biochemistry, Human Physiology, Molecular Medicine