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Cell Polarity and Subcellular RNA Localization

  • Dietmar Richter

Part of the Results and Problems in Cell Differentiation book series (RESULTS, volume 34)

Table of contents

  1. Front Matter
    Pages I-XII
  2. Oswald Steward, Paul Worley
    Pages 1-26
  3. Gary J. Bassell, Robert H. Singer
    Pages 41-56
  4. Jim Eberwine, Christy Job, Janet Estee Kacharmina, Kevin Miyashiro, Stavros Therianos
    Pages 57-67
  5. John H. Carson, Hongyi Cui, Winfried Krueger, Boris Schlepchenko, Craig Brumwell, Elisa Barbarese
    Pages 69-81
  6. Stefan Kindler, Evita Mohr, Monika Rehbein, Dietmar Richter
    Pages 83-104
  7. Alejandra Gardiol, Claudia Racca, Antoine Triller
    Pages 105-128
  8. Yingqun Huang, Gordon G. Carmichael
    Pages 139-155
  9. Kinneret Rand, Joel Yisraeli
    Pages 157-173
  10. Harald Wodrich, Hans-Georg Kräusslich
    Pages 197-217
  11. Back Matter
    Pages 219-221

About this book

Introduction

Selective cytoplasmic organelle and protein targeting has long been thought to constitute the sole determinant of cell polarity and complexity. This view has been changed, however, by the discovery of differential subcellular RNA distribution patterns. Over the past decade it has become clear that selective mRNA sorting and translation contributes to an accumulation of cognate proteins at discrete cellular sites. In this book, various systems are discussed (e.g. Xenopus oocytes, mammalian brain, invertebrate nervous system) in terms of RNA trafficking, RNA-targeting sequences (cis-elements) and RNA-transporting proteins (trans-factors), activity-dependent translational regulation and the significance of the cytoskeleton for neuronal function and plasticity. It also discusses nucleocytoplasmic export of mRNA and viral RNA as another example of subcellular RNA kinesis.

Keywords

Nervous System Organelle RNA RNA Localization RNA Transport Viruses cell nucleus evolution gene expression genes neurons proteins regulation transcription translation

Editors and affiliations

  • Dietmar Richter
    • 1
  1. 1.Institut für Zellbiochemie und klinische NeurobiologieUniversitäts-Krankenhaus EppendorfHamburgGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-540-40025-7
  • Copyright Information Springer-Verlag Berlin Heidelberg 2001
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-07436-3
  • Online ISBN 978-3-540-40025-7
  • Series Print ISSN 0080-1844
  • Series Online ISSN 1861-0412
  • Buy this book on publisher's site