Vogel and Motulsky's Human Genetics

  • Michael R. Speicher
  • Arno G. Motulsky
  • Stylianos E. Antonarakis

Table of contents

  1. Front Matter
    Pages i-liii
  2. Pages 1-12
  3. Arno G. Motulsky
    Pages 13-29
  4. Stylianos E. Antonarakis
    Pages 31-53
  5. Michael R. Speicher
    Pages 55-138
  6. Michael R. Speicher
    Pages 139-163
  7. Arno G. Motulsky
    Pages 165-209
  8. Arno G. Motulsky, Michael Dean
    Pages 211-241
  9. Jon F. Robinson, Nicholas Katsanis
    Pages 243-262
  10. Bernhard Horsthemke
    Pages 299-318
  11. Stylianos E. Antonarakis, David N. Cooper
    Pages 319-363
  12. George P. Patrinos, Stylianos E. Antonarakis
    Pages 365-401
  13. Alexandre Alcaïs Laurent Abel, Jean-Laurent Casanova
    Pages 403-415
  14. Stefan Mundlos
    Pages 417-450
  15. Ian Tomlinson
    Pages 451-470
  16. Romulo Martin Brena, Joseph F. Costello
    Pages 471-486
  17. Emmanouil T. Dermitzakis
    Pages 487-506
  18. Michael Hofreiter
    Pages 529-555
  19. Ross C. Hardison
    Pages 557-587
  20. Sohini Ramachandran, Hua Tang, Ryan N. Gutenkunst, Carlos D. Bustamante
    Pages 589-615
  21. Sophia S. Wang, Terri H. Beaty, Muin J. Khoury
    Pages 617-634
  22. Nicole M. Walley, Paola Nicoletti, David B. Goldstein
    Pages 635-647
  23. Michael R. Speicher
    Pages 649-649
  24. Jonathan Flint, Saffron Willis-Owen
    Pages 651-661
  25. David L. Nelson
    Pages 663-680
  26. Brett S. Abrahams, Daniel H. Geschwind
    Pages 699-714
  27. David Goldman, Francesca Ducci
    Pages 715-741
  28. Michael R. Speicher
    Pages 743-757
  29. Markus M. Nöthen, Sven Cichon, Christine Schmael, Marcella Rietschel
    Pages 759-776
  30. Michael R. Speicher
    Pages 777-777
  31. Antonio Baldini
    Pages 779-785
  32. Ruth Johnson, Ross Cagan
    Pages 795-811
  33. Heidi G. Parker, Elaine A. Ostrander
    Pages 813-826
  34. Siew Hong Lam, Zhiyuan Gong
    Pages 827-843
  35. Tiemo Grimm, Klaus Zerres
    Pages 845-866
  36. Vivian W. Choi, R. Jude Samulski
    Pages 867-874
  37. Ian Wilmut, Jane Taylor, Paul de Sousa, Richard Anderson, Christopher Shaw
    Pages 875-883
  38. David J. Weatherall
    Pages 885-902
  39. Stylianos E. Antonarakis
    Pages 903-903
  40. Rachel A. Harte, Donna Karolchik, Robert M. Kuhn, W. James Kent, David Haussler
    Pages 905-921
  41. Xosé M. Fernández, Ewan Birney
    Pages 923-939
  42. Roberta A. Pagon, Ada Hamosh, Johan den Dunnen, Helen V. Firth, Donna R. Maglott, Stephen T. Sherry et al.
    Pages 941-960
  43. Back Matter
    Pages 961-981

About this book


The fourth, completely revised edition of this classic reference and textbook presents a cohesive and up-to-date exposition of the concepts, results, and problems underlying theory and practice in human and medical genetics. In the 10 years since the appearance of the third edition, many new insights have emerged for understanding the genetic basis of development and function in human health and disease. Human genetics, with its emphasis on molecular concepts and techniques, has become a key discipline in medicine and the biomedical sciences.

The fourth edition has been extensively expanded by new chapters on timely topics such as epigenetics, pharmacogenetics, gene therapy, cloning, and genetic epidemiology, and databases for basic and clinical genetics. In addition a multi/chapter section giving an overview on the main model organisms (mouse, dog, worm, fly, fish) used in human genetics research has been introduced.

This book will be of interest to human and medical geneticists, scientists in all biomedical sciences, physicians and epidemiologists, as well as to graduate and postgraduate students who desire to learn the fundamentals of this fascinating field.


Chromosom Mutation cancer chromosome development epidemiology epigenetics evolution gene therapy genes genetic epidemiology genetics genomics health human evolution

Editors and affiliations

  • Michael R. Speicher
    • 1
  • Arno G. Motulsky
    • 2
  • Stylianos E. Antonarakis
    • 3
  1. 1.Institute of Human GeneticsMedical University of GrazGrazAustria
  2. 2.Departments of Medicine (Division of Medical Genetics) and Genome SciencesUniversity of Washington School of MedicineSeattleUSA
  3. 3.Department of Genetic Medicine and DevelopmentUniversity of Geneva Medical School and University Hospitals of GenevaGenevaSwitzerland

Bibliographic information