Vogel and Motulsky's Human Genetics

  • Michael R. Speicher
  • Arno G. Motulsky
  • Stylianos E. Antonarakis

Table of contents

  1. Front Matter
    Pages i-liii
  2. Pages 1-12
  3. Arno G. Motulsky
    Pages 13-29
  4. Stylianos E. Antonarakis
    Pages 31-53
  5. Michael R. Speicher
    Pages 55-138
  6. Michael R. Speicher
    Pages 139-163
  7. Arno G. Motulsky
    Pages 165-209
  8. Arno G. Motulsky, Michael Dean
    Pages 211-241
  9. Jon F. Robinson, Nicholas Katsanis
    Pages 243-262
  10. Bernhard Horsthemke
    Pages 299-318
  11. Stylianos E. Antonarakis, David N. Cooper
    Pages 319-363
  12. George P. Patrinos, Stylianos E. Antonarakis
    Pages 365-401
  13. Alexandre Alcaïs Laurent Abel, Jean-Laurent Casanova
    Pages 403-415
  14. Stefan Mundlos
    Pages 417-450
  15. Ian Tomlinson
    Pages 451-470
  16. Romulo Martin Brena, Joseph F. Costello
    Pages 471-486
  17. Emmanouil T. Dermitzakis
    Pages 487-506

About this book


The fourth, completely revised edition of this classic reference and textbook presents a cohesive and up-to-date exposition of the concepts, results, and problems underlying theory and practice in human and medical genetics. In the 10 years since the appearance of the third edition, many new insights have emerged for understanding the genetic basis of development and function in human health and disease. Human genetics, with its emphasis on molecular concepts and techniques, has become a key discipline in medicine and the biomedical sciences.

The fourth edition has been extensively expanded by new chapters on timely topics such as epigenetics, pharmacogenetics, gene therapy, cloning, and genetic epidemiology, and databases for basic and clinical genetics. In addition a multi/chapter section giving an overview on the main model organisms (mouse, dog, worm, fly, fish) used in human genetics research has been introduced.

This book will be of interest to human and medical geneticists, scientists in all biomedical sciences, physicians and epidemiologists, as well as to graduate and postgraduate students who desire to learn the fundamentals of this fascinating field.


Chromosom Mutation cancer chromosome development epidemiology epigenetics evolution gene therapy genes genetic epidemiology genetics genomics health human evolution

Editors and affiliations

  • Michael R. Speicher
    • 1
  • Arno G. Motulsky
    • 2
  • Stylianos E. Antonarakis
    • 3
  1. 1.Institute of Human GeneticsMedical University of GrazGrazAustria
  2. 2.Departments of Medicine (Division of Medical Genetics) and Genome SciencesUniversity of Washington School of MedicineSeattleUSA
  3. 3.Department of Genetic Medicine and DevelopmentUniversity of Geneva Medical School and University Hospitals of GenevaGenevaSwitzerland

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-540-37654-5
  • Copyright Information Springer-Verlag Berlin Heidelberg 2010
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-540-37653-8
  • Online ISBN 978-3-540-37654-5
  • About this book