Cell Cycle and Cell Differentiation

  • J. Reinert
  • Howard Holtzer

Part of the Results and Problems in Cell Differentiation book series (RESULTS, volume 7)

Table of contents

  1. Front Matter
    Pages I-XI
  2. S. R. Dienstman, H. Holtzer
    Pages 1-25
  3. Harold Weintraub
    Pages 27-42
  4. Creighton H. Phelps, S. E. Pfeiffer
    Pages 63-83
  5. Armin C. Braun
    Pages 177-196
  6. R. Tsanev
    Pages 197-248
  7. Thaddeus W. Borun
    Pages 249-290
  8. R. E. Nelson, C. P. Selitrennikoff, R. W. Siegel
    Pages 291-310
  9. Back Matter
    Pages 311-334

About this book


It is instructive to compare the response of biologists to the two themes that comprise the title of this volume. The concept of the cell cycle-in contra­ distinction to cell division-is a relatively recent one. Nevertheless biologists of all persuasions appreciate and readily agree on the central problems in this area. Issues ranging from mechanisms that initiate and integrate the synthesis of chro­ mosomal proteins and DNA during S-phase of mitosis to the manner in which assembly of microtubules and their interactions lead to the segregation of metaphase chromosomes are readily followed by botanists and zoologists, as well as by cell and molecular biologists. These problems are crisp and well-defined. The current state of "cell differentiation" stands in sharp contrast. This, one of the oldest problems in experimental biology, almost defies definition today. The difficulties arise not only from a lack of pertinent information on the regulatory mechanisms, but also from conflicting basic concepts in this field. One of the ways in which this situation might be improved would be to find a broader experimental basis, including a better understanding of the relationship between the cell cycle and cell differentiation.


DNA Zelldifferenzierung biology cell cell cycle cell differentiation cell division chromosome proteins

Editors and affiliations

  • J. Reinert
  • Howard Holtzer
    • 1
  1. 1.Department of AnatomyUniversity of PennsylvaniaPhiladelphiaUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-540-37390-2
  • Copyright Information Springer-Verlag Berlin Heidelberg 1975
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-662-21693-4
  • Online ISBN 978-3-540-37390-2
  • Series Print ISSN 0080-1844
  • Series Online ISSN 1861-0412
  • About this book