Breast Cancer and Molecular Medicine

  • Martine J. Piccart
  • Mien-Chie Hung
  • Lawrence J. Solin
  • Fatima Cardoso
  • William C. Wood

Table of contents

  1. Front Matter
    Pages I-LV
  2. Section 1

    1. Front Matter
      Pages 1-1
    2. Larry Norton, Clifford Hudis
      Pages 3-27
  3. Section 2

    1. Front Matter
      Pages 29-30
    2. Thomas Yang, K. S. Clifford Chao
      Pages 42-60
  4. Section 3

    1. Front Matter
      Pages 61-62
    2. Monica Morrow, V. Craig Jordan
      Pages 63-94
  5. Section 4

    1. Front Matter
      Pages 95-95
    2. Philip Meijnen, Johannes L. Peterse, Marc J. van de Vijver
      Pages 97-123
    3. Laura Esserman, Catherine Park
      Pages 125-135
    4. Joyce A. O’Shaughnessy
      Pages 137-156
  6. Section 5

    1. Front Matter
      Pages 157-157
    2. Tara L. Huston, Rache M. Simmons
      Pages 199-213
  7. Section 6

About this book


Molecular-based medicine is taking center stage due to the increasing knowledge of breast cancer molecular biology. Treatment tailoring is no longer a dream for the future, but the main goal of current research.

This book provides an overview of the most recent techniques, agents and approaches for breast cancer that contribute to the individualization of treatment. Current biomedical research focuses on facilitating the transfer of molecular biology knowledge into the clinical management of patients, leading to increased survival as well as improved quality of life. Particular attention is given in this book to organ-specific tailored approaches, specific populations, patients’ preferences and rehabilitation. Also discussed in depth are the respective roles of pharmacotherapeutics modelling, functional imaging, molecular staging, genomics and proteomics and their impact on the "re-classification" of breast cancer, as well as the clinical applications of basic science. The crucial issue of how to optimally integrate biological markers, new technologies and new diagnostic and therapeutic approaches into clinical trials and clinical practice is addressed.

Combining the contributions from authors who are well known experts in these fields with editorial comments, this book provides an overview of the latest achievements in breast cancer and their use in clinical practice.


Biology Breast Cancer Genomics Staging Tailoring angiogenesis apoptosis carcinoma classification imaging positron emission tomography rehabilitation surgery systemic therapy

Editors and affiliations

  • Martine J. Piccart
    • 1
  • Mien-Chie Hung
    • 2
  • Lawrence J. Solin
    • 3
  • Fatima Cardoso
    • 1
  • William C. Wood
    • 4
  1. 1.Dept. of Medical OncologyJules Bordet InstituteBrusselsBelgium
  2. 2.Anderson Cancer CenterThe University of Texas MDHoustonUSA
  3. 3.Dept. of Radiation OncologyHospital of the University of PennsylvaniaPhiladelphiaUSA
  4. 4.Dept. of SurgeryEmory University HospitalAtlantaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2006
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine
  • Print ISBN 978-3-540-28265-5
  • Online ISBN 978-3-540-28266-2
  • About this book