Biophysical Regulation of Vascular Differentiation and Assembly

  • Sharon Gerecht

Part of the Biological and Medical Physics, Biomedical Engineering book series (BIOMEDICAL)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Barak Zohar, Shira Landau, Shulamit Levenberg
    Pages 37-49
  3. Patrícia R. Pitrez, Helena R. Aires, Inês Tomé, Rita Sá Ferreira, Lino Ferreira
    Pages 51-72
  4. Michael R. Blatchley, Hasan E. Abaci, Donny Hanjaya-Putra, Sharon Gerecht
    Pages 73-119
  5. Enoch Yeung, Pooja Yesantharao, Chin Siang Ong, Narutoshi Hibino
    Pages 121-139
  6. Justin Morrissette-McAlmon, Robert N. Hawthorne, Shawna Snyder, Warren L. Grayson
    Pages 141-175
  7. Lina R. Nih, Stanley T. Carmichael, Tatiana Segura
    Pages 177-187
  8. Back Matter
    Pages 189-195

About this book


This book updates and expands on various aspects of the vasculature’s microenvironment and how these regulate differentiation and assembly. Discussed in this new edition are efforts to capitalize on combining engineering techniques, to study and manipulate various biophysical cues, including: endothelial cell-pericyte interactions (Davis), mechanical forces to regulate vascularization in three-dimensional constructs (Levenberg), how matrix properties and oxygen tension regulate vascular fate and assembly (Gerecht), biophysical cues in relation to vascular aging (Ferreira), 3D printing of complex vascularized tissue (Hibino), the harnessing of biophysical cues for therapeutic vasculature interfacing with the damaged brain (Segura) and finally, the infarcted heart (Grayson).

This second edition of Biophysical Regulation of Vascular Differentiation and Assembly provides an interdisciplinary view of vasculature regulation through various biophysical cues and presents recent advances in measuring and controlling such parameters. This book will be of interest to biologists, biophysicists and engineers who work with vascular differentiation and assembly.


biophysics of vascular regulation stem cell engineering stem cells for therapeutic use vascular differentiation vascular surface topography

Editors and affiliations

  • Sharon Gerecht
    • 1
  1. 1.Department of Chemical and Biomolecular EngineeringJohns Hopkins Physical Sciences–Oncology Center and Institute for NanoBioTechnologyBaltimoreUSA

Bibliographic information