Endocytosis and Signaling

  • Christophe Lamaze
  • Ian Prior

Part of the Progress in Molecular and Subcellular Biology book series (PMSB, volume 57)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Noga Budick-Harmelin, Marta Miaczynska
    Pages 39-63
  3. Francesc Tebar, Carlos Enrich, Carles Rentero, Thomas Grewal
    Pages 65-105
  4. Simona M. Migliano, David Teis
    Pages 107-135
  5. Geoffrey G. Hesketh, Lena Wartosch, Luther J. Davis, Nicholas A. Bright, J. Paul Luzio
    Pages 151-180
  6. Rachel Moore, Marta Giralt Pujol, Zhou Zhu, Elizabeth Smythe
    Pages 181-202
  7. Olivia Muriel, Miguel Sánchez-Álvarez, Raffaele Strippoli, Miguel Angel del Pozo
    Pages 203-234
  8. Giusi Caldieri, Maria Grazia Malabarba, Pier Paolo Di Fiore, Sara Sigismund
    Pages 235-272
  9. Alicia Daeden, Marcos Gonzalez-Gaitan
    Pages 301-329

About this book


This book focuses on the context dependency of cell signaling by showing how the endosomal system helps to structure and regulate signaling pathways. The location and concentration of signaling nodes regulate their activation cycles and engagement with distinct effector pathways. Whilst many cell signaling pathways are initiated from the cell surface, endocytosis provides an opportunity for modulating signaling networks’ output. 

In this book, first a series of reviews describe the endocytic and endosomal system and show how these subcellular platforms sort and regulate a wide range of signaling pathway components and phenotypic outputs. The book then reviews the latest scientific insights into how endocytic trafficking and subcellular location modulate a set of major pathways that are essential to normal cellular function and organisms’ development.  


cell signaling endocytosis endosome transmembrane receptor vesicle endocytic trafficking lysosomes caveolae

Editors and affiliations

  • Christophe Lamaze
    • 1
  • Ian Prior
    • 2
  1. 1.Membrane Dynamics and Mechanics of Intracellular Signaling Laboratory, CNRS UMR3666, INSERM U1143, Institut Curie—Centre de RecherchePSL Research UniversityParisFrance
  2. 2.Department of Cellular and Molecular Physiology, Institute of Translational MedicineUniversity of LiverpoolLiverpoolUnited Kingdom

Bibliographic information