Flow Chemistry for the Synthesis of Heterocycles

  • Upendra K. Sharma
  • Erik V. Van der Eycken

Part of the Topics in Heterocyclic Chemistry book series (TOPICS, volume 56)

Table of contents

  1. Front Matter
    Pages i-vii
  2. Seger Van Mileghem, Cedrick Veryser, Wim M. De Borggraeve
    Pages 133-159
  3. Ryan J. Sullivan, Stephen G. Newman
    Pages 161-186
  4. Joachim Demaerel, Vidmantas Bieliūnas, Wim M. De Borggraeve
    Pages 237-317
  5. Andrew R. Bogdan, Michael G. Organ
    Pages 319-341
  6. Md Taifur Rahman, Thomas Wirth
    Pages 343-373
  7. Back Matter
    Pages 391-397

About this book


This volume provides an overview of recent developments and scope in the use of flow chemistry in relevance to heterocyclic synthesis. The heterocyclic ring is the most prominent structural motif in the vast majority of natural products as well as pharmaceutical compounds since this facilitates tuneable interactions with the biological target besides conferring a degree of structural and metabolic stability. In recent times, flow chemistry has heralded a paradigm shift in organic synthesis as it offers several unique advantages over conventional methods like drastic acceleration of sluggish transformations, enhanced yields, cleaner reactions etc and is gradually gaining a lot of attention among organic chemist worldwide. Given the importance of heterocycles in natural products, medicinal chemistry and pharmaceuticals, this is a well warranted volume and complements the previous volume of Topics in Organometallic Chemistry ‘Organometallic Flow Chemistry’.

This volume offers a versatile overview of the topic, besides discussing the recent progress in the flourishing area of flow chemistry in relevance to heterocyclic chemistry; it will also help researchers to better understand the chemistry behind these reactions. This in turn provides a platform for future innovations towards the designing of novel transformations under continuous flow. Thus, this volume will appeal to both the novices in this field as well as to experts in academia and industry.


saturated heterocyclic structures photoredox catalysis MCR strategies Microfluidic devices Flow chemistry heterocyclic synthesis

Editors and affiliations

  • Upendra K. Sharma
    • 1
  • Erik V. Van der Eycken
    • 2
  1. 1.Department of ChemistryUniversity of Leuven (KU Leuven)LeuvenBelgium
  2. 2.Department of ChemistryUniversity of Leuven (KU Leuven)LeuvenBelgium

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG, part of Springer Nature 2018
  • Publisher Name Springer, Cham
  • eBook Packages Chemistry and Materials Science
  • Print ISBN 978-3-319-94327-5
  • Online ISBN 978-3-319-94328-2
  • Series Print ISSN 1861-9282
  • Series Online ISSN 1861-9290
  • Buy this book on publisher's site