Management of Hypertension

Current Practice and the Application of Landmark Trials

  • Vasilios Papademetriou
  • Emmanuel A. Andreadis
  • Charalampia Geladari

Table of contents

  1. Front Matter
    Pages i-xxiii
  2. Introduction to Medical Research

    1. Front Matter
      Pages 1-1
    2. Konstantinos I. Bougioukas, Anna-Bettina Haidich
      Pages 19-53
  3. Major Trials in Hypertension Research and Their Application in Clinical Practice

    1. Front Matter
      Pages 55-55
    2. Vasilios Papademetriou, Michael Doumas, Costas Tsioufis, Kyriakos Dimitriadis, Charles Faselis
      Pages 75-88
    3. K. Dimitriadis, C. Filippou, C. Tsioufis
      Pages 89-100
    4. Samar A. Nasser, Keith C. Ferdinand
      Pages 101-113
    5. Michael Doumas, George L. Bakris
      Pages 115-133
    6. Pedro A. Jose, Van Anthony M. Villar
      Pages 135-143
    7. Ping Li, Annise K. Chung, Samir S. Patel, Vasilios Papademetriou
      Pages 145-154
    8. Nikolaos Magkas, Athanasia Kapota, Costas Tsioufis
      Pages 155-182
    9. Takeshi Fujiwara, Kazuomi Kario
      Pages 183-214
    10. William J. Kostis, Jeanne M. Dobrzynski, John B. Kostis
      Pages 215-238
    11. Emmanuel A. Andreadis, Charalampia V. Geladari
      Pages 239-252
  4. Blood Pressure Assessment Methods Used in Landmark Trials

    1. Front Matter
      Pages 253-253
  5. Pioneers in Hypertension Research

  6. Future Perspectives in Cardiovascular Research

About this book


This book is a valuable tool to assist both cardiovascular physicians and scientists learning the intricacies of hypertension research and its milestone studies. All major hypertension trials have been reviewed in this book in chronological order with extensive discussion of the study population, study design, and outcomes and with a special focus on what knowledge they offered, their strengths and weaknesses, statistical errors, impact on international guidelines and unmet needs. Importantly, the book also offers physicians and young scientists with basic knowledge regarding medical biostatistics. It is of critical importance for a scientist involved in the field to understand deeply the process of analysing medical data. Moreover, the accurate interpretation of the results is central for applying evidence-based medicine in everyday clinical practice.

Management of Hypertension: Current Practice and the Application of Landmark Trials is a critical tool to assist in the education of physicians and researchers in the field, providing a separate section on pioneer researchers in hypertension and urging readers to become bright exemplars for scientists wishing to pursue a career in academic medicine and hypertension research.


Evidence based medicine Hypertension Landmark studies Biostatistical weaknesses Effect on Guidelines Pioneers in hypertension research

Editors and affiliations

  • Vasilios Papademetriou
    • 1
  • Emmanuel A. Andreadis
    • 2
  • Charalampia Geladari
    • 3
  1. 1.Georgetown University and VA Medical CenterWashington, DCUSA
  2. 2.Fourth Internal Medicine DepartmentEvangelismos State General HospitalAthensGreece
  3. 3.Fourth Internal Medicine DepartmentEvangelismos State General HospitalAthensGreece

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG, part of Springer Nature 2019
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-319-92945-3
  • Online ISBN 978-3-319-92946-0
  • Buy this book on publisher's site