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Textbook of Energy Balance, Neuropeptide Hormones, and Neuroendocrine Function

  • Eduardo A. Nillni

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Evolution and Origens of Obesity

  3. The Hypothalamus

    1. Front Matter
      Pages 27-27
    2. Eduardo A. Nillni
      Pages 29-54
    3. Isin Cakir, Eduardo A. Nillni
      Pages 75-108
    4. Eduardo A. Nillni
      Pages 109-139
    5. Isin Cakir, Eduardo A. Nillni
      Pages 141-180
  4. Peripheral Contributors Participating in Energy Homeostasis and Obesity

    1. Front Matter
      Pages 181-181
    2. María F. Andreoli, Pablo N. De Francesco, Mario Perello
      Pages 183-203
    3. Katie M. Troike, Kevin Y. Lee, Edward O. List, Darlene E. Berryman
      Pages 205-223
    4. Hyokjoon Kwon, Jeffrey E. Pessin
      Pages 225-252
  5. Neuroendocrine Axes and Obesity

    1. Front Matter
      Pages 253-253
    2. Sara Singhal, Jennifer W. Hill
      Pages 271-319
    3. Brooke Henry, Elizabeth A. Jensen, Edward O. List, Darlene E. Berryman
      Pages 321-344
  6. Nutrition

    1. Front Matter
      Pages 345-345
    2. Kyle S. Burger, Grace E. Shearrer, Jennifer R. Gilbert
      Pages 347-369
  7. Back Matter
    Pages 371-378

About this book

Introduction

This textbook presents for the first time a comprehensive body of the latest knowledge in the field of neuropeptides and their action on energy balance. It contains a detailed and comprehensive account of the specific hypothalamic peptides in regards to their roles in energy balance, food intake control and co-morbidities, to better understand the patho-physiology of obesity.
The textbook includes an examination the history of the evolution of human society from a thin to the obese phenotype and, within that context, how modern society habits and industrial food production did not respect the evolutionary trait resulting in changes in the energy balance set point. It provides a novel conceptualization of the problem of obesity when considering the biochemistry of peptide hormones and entertaining novel ideas on multiple approaches to the problems of energy balance, as well as demonstrates and explains why alterations in pro-hormone processing are paramount to understand metabolic disease. 
This text is excellent material for teaching graduate and medical school courses, as well as a valuable resource for researchers in biochemistry, cell, and molecular biology, neuroscientists, physician endocrinologists, and nutritionists.

Keywords

nutrient sensors thyrotropin releasing hormone endoplasmic reticulum stress leptin obesity prohormones neuroendocrinology

Editors and affiliations

  • Eduardo A. Nillni
    • 1
  1. 1.Emeritus Professor of Medicine, Molecular Biology, Cell Biology & Biochemistry, Department of Medicine, Molecular Biology, Cell Biology & BiochemistryThe Warren Alpert Medical School of Brown UniversityProvidenceUSA

Bibliographic information