Island of Reil (Insula) in the Human Brain

Anatomical, Functional, Clinical and Surgical Aspects

  • Mehmet Turgut
  • Canan Yurttaş
  • R. Shane Tubbs

Table of contents

  1. Front Matter
    Pages i-xi
  2. Anatomy of the Human Insula

    1. Front Matter
      Pages 1-1
    2. Yigit Uyanikgil, Turker Cavusoglu, Servet Celik, Kubilay Dogan Kilic, Mehmet Turgut
      Pages 3-13
    3. Igor Lima Maldonado, Ilyess Zemmoura, Christophe Destrieux
      Pages 15-22
    4. Christophe Destrieux, Igor Lima Maldonado, Louis-Marie Terrier, Ilyess Zemmoura
      Pages 23-37
    5. Servet Celik, Okan Bilge, Canan Yurttaş, Mehmet Turgut
      Pages 39-53
    6. Servet Celik, Okan Bilge, Mehmet Turgut, Canan Yurttaş
      Pages 55-69
    7. Igor Lima Maldonado, Ilyess Zemmoura, Christophe Destrieux
      Pages 71-75
    8. Jimmy Ghaziri, Dang Khoa Nguyen
      Pages 77-83
    9. Hasan Emre Aydın, İsmail Kaya
      Pages 85-90
    10. Ersen Ertekin, Özüm Tunçyürek, Mehmet Turgut, Yelda Özsunar
      Pages 91-100
    11. Niyazi Acer, Mehmet Turgut
      Pages 101-111
    12. Yuri Terasawa, Satoshi Umeda
      Pages 113-120
  3. Functions of the Human Insula

    1. Front Matter
      Pages 121-121
    2. Alfredo Ardila
      Pages 123-128
    3. Michael J. Montalbano, R. Shane Tubbs
      Pages 129-132
    4. Richard J. Stevenson, Heather M. Francis, Cameron J. Ragg
      Pages 133-145
    5. Oreste de Divitiis, Teresa Somma, D’Urso Giordano, Mehmet Turgut, Paolo Cappabianca
      Pages 147-149
    6. Seong-Jin Moon, Lara Tkachenko, Erick Garcia-Gorbea, R. Shane Tubbs, Marc D. Moisi
      Pages 157-159
    7. Paul Choi, Emily Simonds, Marc Vetter, Charlotte Wilson, R. Shane Tubbs
      Pages 169-174
    8. Christoph J. Griessenauer, Raghav Gupta
      Pages 175-178
  4. Clinical Disorders Related with Insula

    1. Front Matter
      Pages 195-195
    2. Manish Jaiswal
      Pages 197-202
    3. Bing Yu Chen, Olivier Boucher, Christian Dugas, Dang Khoa Nguyen, Laura Gioia
      Pages 203-212
    4. Jordi Manuello, Andrea Nani, Franco Cauda
      Pages 213-221
    5. Olivier Boucher, Daphné Citherlet, Benjamin Hébert-Seropian, Dang Khoa Nguyen
      Pages 223-238
    6. Cameron Schmidt
      Pages 239-251
  5. Surgery of the Insular Cortex

    1. Front Matter
      Pages 253-253
    2. Karine Michaud, Hugues Duffau
      Pages 255-262
    3. Mehmet Turgut, Paulo Roberto Lacerda Leal, Evelyne Emery
      Pages 263-269
    4. Vamsi Krishna Yerramneni, Alain Bouthillier, Dang Khoa Nguyen
      Pages 271-280
    5. Barbara Tomasino, Dario Marin, Tamara Ius, Miran Skrap
      Pages 281-292
  6. Back Matter
    Pages 293-298

About this book


This book provides an in-depth review of the insula, with emphasis on anatomical, diagnostics, clinical, and surgical features. The insular cortex is involved in a variety of functions, but a comprehensive resource cataloging these functions is not available in the current literature. This book gathers highly informative chapters written and edited by leading international authorities in the field and covers the full range of the insular cortex, approaching it in four main sections: firstly, the embryology and anatomy of the human insula; secondly, the functions of the human insula, including its role in nociception, language, decision making, cognition, emotional awareness etc.; thirdly, clinical disorders related to the insula such as epilepsy, schizophrenia, and Parkinson’s disease; and fourthly, surgical techniques for insular gliomas and temporal lobe epilepsy. This comprehensive reference book will be an ideal source for neurosurgeons, neurologists and neuroanatomists seeking both basic and more advanced information regarding this unique structure in the human brain.


Insula cortex Nociception Decision making Epilepsy Schizophrenia Parkinson’s disease Neuroimaging

Editors and affiliations

  • Mehmet Turgut
    • 1
  • Canan Yurttaş
    • 2
  • R. Shane Tubbs
    • 3
  1. 1.Adnan Menderes University, School of Medicine AydınTurkey
  2. 2.Ege University, Department of AnatomyIzmirTurkey
  3. 3.Seattle Science FoundationSeattleUSA

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG, part of Springer Nature 2018
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-319-75467-3
  • Online ISBN 978-3-319-75468-0
  • Buy this book on publisher's site