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A Metaheuristic Approach to Protein Structure Prediction

Algorithms and Insights from Fitness Landscape Analysis

  • Nanda Dulal Jana
  • Swagatam Das
  • Jaya Sil

Part of the Emergence, Complexity and Computation book series (ECC, volume 31)

Table of contents

  1. Front Matter
    Pages i-xxix
  2. Nanda Dulal Jana, Swagatam Das, Jaya Sil
    Pages 1-28
  3. Nanda Dulal Jana, Swagatam Das, Jaya Sil
    Pages 29-38
  4. Nanda Dulal Jana, Swagatam Das, Jaya Sil
    Pages 39-85
  5. Nanda Dulal Jana, Swagatam Das, Jaya Sil
    Pages 87-150
  6. Nanda Dulal Jana, Swagatam Das, Jaya Sil
    Pages 169-195
  7. Nanda Dulal Jana, Swagatam Das, Jaya Sil
    Pages 197-206
  8. Nanda Dulal Jana, Swagatam Das, Jaya Sil
    Pages 207-209
  9. Back Matter
    Pages 211-220

About this book

Introduction

This book introduces characteristic features of the protein structure prediction (PSP) problem. It focuses on systematic selection and improvement of the most appropriate metaheuristic algorithm to solve the problem based on a fitness landscape analysis, rather than on the nature of the problem, which was the focus of methodologies in the past.

 Protein structure prediction is concerned with the question of how to determine the three-dimensional structure of a protein from its primary sequence. Recently a number of successful metaheuristic algorithms have been developed to determine the native structure, which plays an important role in medicine, drug design, and disease prediction.

 This interdisciplinary book consolidates the concepts most relevant to protein structure prediction (PSP) through global non-convex optimization. It is intended for graduate students from fields such as computer science, engineering, bioinformatics and as a reference for researchers and practitioners.

Keywords

Protein Structure Prediction PSP AB off-lattice Model Fitness Landscape Analysis Metaheuristic Algorithms

Authors and affiliations

  • Nanda Dulal Jana
    • 1
  • Swagatam Das
    • 2
  • Jaya Sil
    • 3
  1. 1.Department of Computer Science and EngineeringNational Institute of Technology DurgapurDurgapurIndia
  2. 2.Indian Statistical InstituteElectronics and Communication Sciences UnitKolkataIndia
  3. 3.Department of Computer Science and TechnologyIndian Institute of Engineering Science and TechnologyHowrahIndia

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-74775-0
  • Copyright Information Springer International Publishing AG 2018
  • Publisher Name Springer, Cham
  • eBook Packages Engineering
  • Print ISBN 978-3-319-74774-3
  • Online ISBN 978-3-319-74775-0
  • Series Print ISSN 2194-7287
  • Series Online ISSN 2194-7295
  • Buy this book on publisher's site