Extraskeletal Effects of Vitamin D

A Clinical Guide

  • Emilia Pauline┬áLiao

Part of the Contemporary Endocrinology book series (COE)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Daniel D. Bikle
    Pages 1-40
  3. Shir Azrielant, Yehuda Shoenfeld
    Pages 41-55
  4. Christian Wejse, Cecilie Blenstrup Patsche
    Pages 57-75
  5. Caleb Killer, Jungmi Ahn, Sulgi Park, Bandana Chatterjee
    Pages 77-101
  6. Albert Do, Petr Protiva
    Pages 103-114
  7. Geoffrey Brown, Andrzej Kutner, Ewa Marcinkowska
    Pages 115-134
  8. Emilia Pauline Liao
    Pages 135-149
  9. Kaushal Sondarwa, Rupinder S. Buttar, Victoria Hensley, Michal L. Melamed
    Pages 151-164
  10. Dimiter Avtanski, Anabel Garcia, Emilia Pauline Liao
    Pages 165-181
  11. Anindita Nandi
    Pages 183-204
  12. Giovanni Iolascon, Antimo Moretti, Letizia Stefano, Francesca Gimigliano
    Pages 205-225
  13. Back Matter
    Pages 249-254

About this book


While the skeletal effects of vitamin D are well-documented, the role and importance of vitamin D outside of bone health has not been well-established. Vitamin D receptors are located in nearly every tissue of the body, and low levels of vitamin D are associated with a range of various diseases.

This book provides an in-depth examination of these extraskeletal effects of vitamin D and the associations between vitamin D deficiency and various disease states. Beginning with a review of the biochemistry and physiology of vitamin D, subsequent chapters investigate its relationship to autoimmune and infectious diseases, various forms of cancer, endocrine issues such as diabetes, obesity and reproductive function, cardiovascular disease and muscle weakness. Concluding chapters discuss the role of vitamin D in neurological disorders, including Alzheimer's Disease, and cognitive function.

Focusing on extraskeletal effects only across a range of conditions, Extraskeletal Effects of Vitamin D will be an important resource for clinical endocrinologists and primary care physicians.


Autoimmune disease Calcitriol Cancer Cardiovascular disease Cognitive function Endocrine disorder Hormonal regulation Hypertension Immune system Infectious disease Insulin resistance Leukemia Muscle weakness Neurological disease Obesity Reproductive disorder Type 2 diabetes Vitamin D

Editors and affiliations

  • Emilia Pauline┬áLiao
    • 1
  1. 1.Lenox Hill HospitalNew YorkUSA

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG, part of Springer Nature 2018
  • Publisher Name Humana Press, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-73741-6
  • Online ISBN 978-3-319-73742-3
  • Series Print ISSN 2523-3785
  • Series Online ISSN 2523-3793
  • Buy this book on publisher's site