Neurodegenerative Diseases

Clinical Aspects, Molecular Genetics and Biomarkers

  • Daniela Galimberti
  • Elio Scarpini

Table of contents

  1. Front Matter
    Pages i-x
  2. Mahdi Ghani, Christiane Reitz, Peter St George-Hyslop, Ekaterina Rogaeva
    Pages 29-50
  3. Céline Bellenguez, Jean-Charles Lambert
    Pages 51-76
  4. Giulia Grande, Davide L. Vetrano, Francesca Mangialasche
    Pages 93-112
  5. Giorgio Giulio Fumagalli
    Pages 113-121
  6. Raffaele Ferrari, Claudia Manzoni, Parastoo Momeni
    Pages 147-186
  7. Lars M. Ittner, Wei S. Lee, Kristie Stefanoska, Prita R. Asih, Yazi D. Ke
    Pages 187-219
  8. Niklas Mattsson, Sotirios Grigoriou, Henrik Zetterberg
    Pages 221-252
  9. Nicola Ticozzi, Vincenzo Silani
    Pages 279-295
  10. L. Bonanni, R. Franciotti, S. Delli Pizzi, A. Thomas, M. Onofrj
    Pages 297-312
  11. Camilla Ferrari, Benedetta Nacmias, Sandro Sorbi
    Pages 313-336
  12. Vanessa Carvalho, Carlota Vicente Cunha, João Massano
    Pages 349-378
  13. Axel Petzold
    Pages 379-400
  14. Back Matter
    Pages 401-407

About this book


This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer’s disease, frontotemporal lobar degeneration, Lewy body dementia,Parkinson’s disease, amyotrophic lateral sclerosis, and additional less common neurodegenerative diseases. Both clinical and basic aspects of each disease are treated, including novel diagnostic criteria, old and new treatments, basic discoveries (genetics, epigenetics and molecular biology), and translation of basic research into biomarkers for early diagnosis, particularly to identify peripheral biomarkers. In addition, emerging data indicate that neurodegeneration seems to also be present in classically non-degenerative disorders. Therefore, a chapter about overlapping mechanisms between dementias and psychiatric disorders is included, as well as a description of the role of neurodegeneration in multiple sclerosis.

Neurodegenerative Diseases is aimed at clinicians, particularly those working in academic hospitals. This multidisciplinary book will also be of interest to basic researchers in medical fields.


Alzheimer's Amyotrophic Lateral Sclerosis Frontotemporal Lobar Degeneration dementia neurodegeneration

Editors and affiliations

  • Daniela Galimberti
    • 1
  • Elio Scarpini
    • 2
  1. 1.University of Milan, Fondazione Ca’ Granda, IRCCS Ospedale PoliclinicoMilanItaly
  2. 2.University of Milan, Fondazione Ca’ Granda, IRCCS Ospedale PoliclinicoMilanItaly

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG, part of Springer Nature 2018
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-72937-4
  • Online ISBN 978-3-319-72938-1
  • Buy this book on publisher's site