The Biology of Early Life Stress

Understanding Child Maltreatment and Trauma

  • Jennie G. Noll
  • Idan Shalev

Part of the Child Maltreatment Solutions Network book series (CMSN)

Table of contents

  1. Front Matter
    Pages i-xx
  2. Jacinda C. Li, Andrea Danese
    Pages 1-14
  3. Jacoba Rock, Charles F. Geier, Jennie G. Noll, Michael D. De Bellis
    Pages 45-56
  4. Olivia Altamirano, Victor G. Carrión
    Pages 71-88
  5. Kan Long, George A. Bonanno
    Pages 121-146
  6. Jennie G. Noll, Idan Shalev
    Pages 147-156
  7. Back Matter
    Pages 157-162

About this book


This innovative collection extends the emerging field of stress biology to examine the effects of a substantial source of early-life stress: child abuse and neglect. Research findings across endocrinology, immunology, neuroscience, and genomics supply new insights into the psychological variables associated with adversity in children and its outcomes. These compelling interdisciplinary data add to a promising model of biological mechanisms involved in individual resilience amid chronic maltreatment and other trauma. At the same time, these results also open out distinctive new possibilities for serving vulnerable children and youth, focusing on preventing, intervening in, and potentially even reversing the effects of chronic early trauma.

Included in the coverage:

  • Biological embedding of child maltreatment
  • Toward an adaptation-based approach to resilience                       
  • Developmental traumatology: brain development and maltreated children with and without PTSD
  • Childhood maltreatment and pediatric PTSD: abnormalities in threat neural circuitry
  • An integrative temporal framework for psychological resilience

The Biology of Early Life Stress is important reading for child maltreatment researchers; clinical psychologists; educators in counseling, psychology, trauma, and nursing; physicians; and state- and federal-level policymakers. Advocates, child and youth practitioners, and clinicians in general will find it a compelling resource.


Biological embedding Child maltreatment Immune functioning Metabolic functioning Child trauma Telomere length Molecular genetics Childhood PTSD Child mental health Child coping Endocrinology Resilience Neurobiology Childhood stress DNA Methylation Lifetime stress Gene expression Epigenetics

Editors and affiliations

  • Jennie G. Noll
    • 1
  • Idan Shalev
    • 2
  1. 1.The Pennsylvania State UniversityUSA
  2. 2.Department of Biobehavioral HealthThe Pennsylvania State UniversityState CollegeUSA

Bibliographic information