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Cardiac Cell Culture Technologies

Microfluidic and On-Chip Systems

  • Zbigniew Brzozka
  • Elzbieta Jastrzebska

Table of contents

  1. Front Matter
    Pages i-xix
  2. Elzbieta Jastrzebska, Zbigniew Brzozka
    Pages 1-2
  3. Sandra Skorupska, Elzbieta Jastrzebska, Michal Chudy, Artur Dybko, Zbigniew Brzozka
    Pages 3-21
  4. Dominika Kalinowska, Katarzyna Tokarska, Ilona Grabowska-Jadach, Artur Dybko, Zbigniew Brzozka
    Pages 23-53
  5. Aleksandra Szuplewska, Michal Chudy, Zbigniew Brzozka
    Pages 55-78
  6. Karolina Archacka, Edyta Brzoska, Maria A. Ciemerych, Areta M. Czerwinska, Iwona Grabowska, Kamil K. Kowalski et al.
    Pages 109-154
  7. Elzbieta Jastrzebska, Zbigniew Brzozka
    Pages 155-167
  8. Magdalena Bulka, Elzbieta Jastrzebska
    Pages 169-199
  9. Anna Kobuszewska, Patrycja Sokolowska, Elzbieta Jastrzebska
    Pages 201-231
  10. Back Matter
    Pages 233-234

About this book

Introduction

  • Microfluidic systems for cardiac cell culture are discussed based on tested cells and the methods of cardiac cell stimulation;
  • The use of stem cell stimulation into cardiac cells in microfluidic systems is discussed in the context of electrical, biochemical, physical, and mechanical stimulations;
  • Provides an overview of the measurements and data that can be extracted from on-chip systems for use in diagnostics, drug discovery and screening, and clinical therapy. 
This book provides an introduction to the biological background of heart functioning and analyzes the various materials and technologies used for the development of microfluidic systems dedicated to cell culture, with an emphasis on cardiac cells. The authors describe the characterization of microfluidic systems for cardiac cell culture and center their discussion of the use of stem cell stimulation based on four different types: electrical, biochemical, physical, and mechanical. This book is appropriate for researchers focused on on-chip technologies and heart studies, students in bioengineering and microengineering courses, and a variety of professionals, such as biotechnologists, biomedical engineers, and clinicians working in the cardiac diseases field.

Keywords

Heart-on-a-chip Lab-on-a-chip Microfluidic systems Heart diseases Cardiac and stem cells Cell differentiation Biochemical stimulation Physical stimulation Mechanical stimulation Monitoring of cell proliferation Toxicity assays Electrical stimulation

Editors and affiliations

  • Zbigniew Brzozka
    • 1
  • Elzbieta Jastrzebska
    • 2
  1. 1.The Chair of Medical Biotechnology, Faculty of ChemistryWarsaw University of TechnologyWarsawPoland
  2. 2.The Chair of Medical Biotechnology, Faculty of ChemistryWarsaw University of TechnologyWarsawPoland

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-70685-6
  • Copyright Information Springer International Publishing AG 2018
  • Publisher Name Springer, Cham
  • eBook Packages Engineering
  • Print ISBN 978-3-319-70684-9
  • Online ISBN 978-3-319-70685-6
  • Buy this book on publisher's site