5-HT2A Receptors in the Central Nervous System

  • Bruno P. Guiard
  • Giuseppe Di Giovanni

Part of the The Receptors book series (REC, volume 32)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Properties and Distribution of the 5-HT2AR

    1. Front Matter
      Pages 1-1
    2. Sylwia Łukasiewicz, Ewa Błasiak, Marta Dziedzicka-Wasylewska
      Pages 57-66
    3. Cristiano Bombardi
      Pages 67-84
  3. 5-HT2AR Related Brain Functions

    1. Front Matter
      Pages 135-135
    2. M. Kermorgant, A. Pavy-Le Traon, J. M. Senard, D. N. Arvanitis
      Pages 137-145
    3. Anna Castañé, Albert Adell
      Pages 191-204
    4. Lucia Moravčíková, Kristína Csatlósová, Barbora Ďurišová, Katarína Ondáčová, Michaela Pavlovičová, Ľubica Lacinová et al.
      Pages 205-230
    5. Alfredo Meneses, Rossana Nieto-Vera, Rosa María Anaya-Jiménez
      Pages 259-271
    6. Cristina Miguelez, Teresa Morera-Herreras, Philippe De Deurwaerdère
      Pages 273-310
    7. Christine Courteix, Amandine Dupuis, Pierre-Yves Martin, Benoit Sion
      Pages 339-352
    8. Philip Gorwood, Laurence Lanfumey, Odile Viltart, Nicolas Ramoz
      Pages 353-373
    9. Vincenzo Crunelli, Marcello Venzi, Philippe De Deurwaerdère, Giuseppe Di Giovanni
      Pages 375-394
    10. Minal Jaggar, Vidita A. Vaidya
      Pages 395-438
  4. Back Matter
    Pages 439-446

About this book


5-HT2A receptors are G-protein coupled receptors that are widely distributed throughout the brain, most notably on neuronal and glial cells. 5-HT2A receptors have been implicated in various central physiological functions including mood regulation, memory, sleep, nociception, eating, and reward behaviors, and they are also believed to control the cardiovascular system. This  book provides a comprehensive overview of these receptors including sections on their properties and distribution, approaches for their study, their role in a number of brain functions and diseases, and their role as therapeutic targets. ​


5HT2A receptors G-protein coupled receptors neuropsychiatric disorders pharmacology physiology trafficking brain imaging schizophrenia Pathophysiology eating disorders epilepsy

Editors and affiliations

  • Bruno P. Guiard
    • 1
  • Giuseppe Di Giovanni
    • 2
  1. 1.Faculté de PharmacieUniversité Paris Sud, Université Paris-SaclayChatenay-MalabryFrance
  2. 2.Department of Physiology and BiochemistryUniversity of MaltaMsida MSDMalta

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG 2018
  • Publisher Name Humana Press, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-70472-2
  • Online ISBN 978-3-319-70474-6
  • Series Print ISSN 1048-6909
  • Series Online ISSN 2524-6488
  • Buy this book on publisher's site