In Vivo Reprogramming in Regenerative Medicine

  • Açelya Yilmazer

Part of the Stem Cell Biology and Regenerative Medicine book series (STEMCELL)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Cansu Gurcan, Hadiseh Taheri, Açelya Yilmazer
    Pages 1-10
  3. Jonathan M. W. Slack
    Pages 31-44
  4. Irene de Lázaro
    Pages 65-82
  5. Hadiseh Taheri, Cansu Gurcan, Açelya Yilmazer
    Pages 99-103

About this book

Introduction

There have been significant improvements in the development of cell based therapies; however, current treatment strategies still suffer from some problems: the need for long in vitro culture conditions, inefficient delivery of cells by scaffolds and low incorporation and grafting efficiencies. Therefore, in vivo reprogramming has emerged as a novel treatment technology. In the process of in vivo reprogramming, cells switch to another cell type within the living organism. Leaders in the field discuss how in vivo reprogramming can be used for tissue repair and regeneration in different organs, including pancreas, liver and heart. Furthermore, recent studies on in vivo cell reprogramming towards pluripotency are also reviewed. Current challenges of these preclinical studies are discussed and hypothesis and suggestions are given in order to improve the current strategies to achieve translation into clinic. 

Keywords

Brain Repair Cardiomyocyte Regeneration Cell Lineage Dedifferation Spinal Cord Injury Tissue Repair

Editors and affiliations

  • Açelya Yilmazer
    • 1
  1. 1.Biomedical Engineering DepartmentAnkara UniversityTandoganTurkey

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-65720-2
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Humana Press, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-65719-6
  • Online ISBN 978-3-319-65720-2
  • Series Print ISSN 2196-8985
  • Series Online ISSN 2196-8993
  • About this book