A Practical Guide for Cancer Immunotherapy

  • Laurence Zitvogel
  • Guido Kroemer

Table of contents

  1. Front Matter
    Pages i-x
  2. Laurence Zitvogel, Guido Kroemer
    Pages 1-2
  3. Fundamentals in I-O

    1. Front Matter
      Pages 3-3
    2. Yann Vano, Nicolas A. Giraldo, Wolf Herman Fridman, Catherine Sautès-Fridman
      Pages 5-21
    3. Weimin Wang, Michael Green, J. Rebecca Liu, Theodore S. Lawrence, Weiping Zou
      Pages 23-39
    4. Martin Rao, Liu Zhenjiang, Qingda Meng, Georges Sinclair, Ernest Dodoo, Markus Maeurer
      Pages 41-67
    5. Thaiz Rivera Vargas, Lionel Apetoh
      Pages 69-95
    6. Anthony R. Cillo, Dario A. A. Vignali
      Pages 97-113
    7. Dipti Vijayan, Mark J. Smyth, Michele W. L. Teng
      Pages 115-141
    8. N. Bendriss-Vermare, N. Gourdin, N. Vey, J. Faget, V. Sisirak, I. Labidi-Galy et al.
      Pages 143-161
    9. Kevin Alicea-Torres, Dmitry I. Gabrilovich
      Pages 181-197
    10. Mélanie Bruchard, Francois Ghiringhelli
      Pages 199-213
    11. Oliver Kepp, Jonathan Pol, Laurence Zitvogel, Guido Kroemer
      Pages 215-229
  4. Breakthrough Status

    1. Front Matter
      Pages 247-247
    2. Cornelis J. M. Melief
      Pages 249-261
    3. Maria Agarwal, Cornelia Trimble
      Pages 263-274
    4. Laura Chiossone, Eric Vivier
      Pages 275-288
    5. George C. Prendergast, William J. Malachowski, Arpita Mondal, Peggy Scherle, Alexander J. Muller
      Pages 289-307
  5. FDA-EMA Approval of I-O

    1. Front Matter
      Pages 309-309
    2. Aurélien Marabelle
      Pages 311-319
    3. Daniel Morgensztern, Roy S. Herbst
      Pages 333-344
    4. Lisa Derosa, Bernard Escudier
      Pages 345-355
    5. Pernelle Lavaud, Yohann Loriot
      Pages 357-369
    6. Nicolas A. Giraldo, Janis M. Taube
      Pages 371-385
    7. Rutika Mehta, Igor Puzanov
      Pages 387-403
  6. Developing Fields

    1. Front Matter
      Pages 405-405
    2. Sho Hangai, Yoshitaka Kimura, Tadatsugu Taniguchi, Hideyuki Yanai
      Pages 407-427
    3. Ignacio Melero, Elisabeth Pérez-Ruiz, Alfonso R. Sanchez-Paulete, Alvaro Teijeira, Angela Aznar, Miguel F. Sanmamed
      Pages 429-446
    4. Mélodie Bonvalet, Romain Daillère, Maria P. Roberti, Conrad Rauber, Laurence Zitvogel
      Pages 447-462
    5. Thomas U. Marron, Linda Hammerich, Joshua Brody
      Pages 463-481
    6. C. Maherzi, F. Onodi, E. Tartour, M. Terme, C. Tanchot
      Pages 483-506
    7. Sandra Demaria, Sophia Bornstein, Silvia C. Formenti
      Pages 507-524
    8. Miles C. Andrews, Jennifer A. Wargo
      Pages 525-544
  7. Changes in Clinical Practice

    1. Front Matter
      Pages 545-545
    2. Sophie Postel-Vinay, Jean-Charles Soria
      Pages 547-563
    3. Lucia Festino, Paolo A. Ascierto
      Pages 565-578
    4. Alexander M. M. Eggermont, Caroline Robert
      Pages 579-591
    5. Wendy Mao, Charles G. Drake
      Pages 593-606
    6. Mathilde Saint-Ghislain, Marie Bretagne, Marie-Paule Sablin, Emanuela Romano
      Pages 607-619
    7. Bertrand Routy, David Ghez
      Pages 641-655
    8. Michael Platten
      Pages 657-664
    9. Mathilde Allard, Michael Hebeisen, Nathalie Rufer
      Pages 665-679
    10. Petra Baumgaertner, Kalliopi Ioannidou, Daniel E. Speiser
      Pages 681-694
    11. Cedrik M. Britten, Laura A. Johnson, Alfonso Quintás-Cardama, Neil C. Sheppard, Axel Hoos
      Pages 695-717
  8. Concluding Remarks

    1. Front Matter
      Pages 719-719
    2. Pedro Romero, Wolf H. Fridman
      Pages 721-724

About this book


In this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status. The aim is to deliver a landmark educational tool that will serve as the definitive reference for MD and PhD students while also meeting the needs of established researchers and healthcare professionals.

Immunotherapy-based approaches are now inducing long-lasting clinical responses across multiple histological types of neoplasia, in previously difficult-to-treat metastatic cancers. The future challenges for oncologists are to understand and exploit the cellular and molecular components of complex immune networks, to optimize combinatorial regimens, to avoid immune-related side effects, and to plan immunomonitoring studies for biomarker discovery. The editors hope that this book will guide future and established health professionals toward the effective application of cancer immunology and immunotherapy and contribute significantly to further progress in the field.


Cancer Immunotherapy Immuno-Oncology Cancer Vaccines Biomarkers Immunopathology

Editors and affiliations

  • Laurence Zitvogel
    • 1
  • Guido Kroemer
    • 2
  1. 1.Gustave Roussy Cancer Center Villejuif CedexFrance
  2. 2.Gustave Roussy Cancer Center Villejuif CedexFrance

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG 2018
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-319-62430-3
  • Online ISBN 978-3-319-62431-0
  • Buy this book on publisher's site