Bone Marrow Failure

  • Gary M. Kupfer
  • Gregory H. Reaman
  • Franklin O. Smith

Part of the Pediatric Oncology book series (PEDIATRICO)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Erinn B. Rankin, Kathleen M. Sakamoto
    Pages 1-23
  3. Yigal Dror, Michaela Cada
    Pages 25-55
  4. Inga Hofmann
    Pages 57-79
  5. Ali Suliman, Franklin O. Smith, Gary M. Kupfer
    Pages 81-97
  6. Anna Aspesi, Steven R. Ellis
    Pages 99-110
  7. Lois Dodson, Alison A. Bertuch
    Pages 111-135
  8. Shilpa M. Hattangadi, Jeffrey M. Lipton
    Pages 137-152
  9. Kasiani C. Myers, Akiko Shimamura
    Pages 153-164
  10. Taizo Nakano, Jorge Di Paola
    Pages 193-214

About this book


This book presents the latest scientific knowledge on inherited and acquired bone marrow failure syndromes, describing the advances in understanding of genetics and pathophysiology that have been achieved as a result of high-throughput DNA sequencing, RNA expression studies, and modern biochemistry techniques. The full range of relevant conditions is covered, including acquired aplastic anemia, Fanconi anemia, ribosomopathies, telomeropathies, dyskeratosis congenita, Shwachman-Diamond syndrome, Diamond-Blackfan anemia, and congenital neutropenias and thrombocytopenias. In addition, it is explained how the study of these rare diseases has uncovered important new science and elucidated the pathophysiology of more common hematological and oncological diseases. A treatment-specific chapter describes options ranging from the conventional to the cutting edge. Bone Marrow Failure will be of value for both trainee and practicing hematologists and oncologists.


Bone Marrow Faillure Aplastic Anemia Telomeropathies Ribosomopathies Fanconi Anemia Isolated Cytopenias

Editors and affiliations

  • Gary M. Kupfer
    • 1
  • Gregory H. Reaman
    • 2
  • Franklin O. Smith
    • 3
  1. 1.Department of PediatricsYale School of MedicineNew HavenUSA
  2. 2.Department of PediatricsGeorge Washington UniversityWashington, DCUSA
  3. 3.MedpaceCincinnatiUSA

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG, part of Springer Nature 2018
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-319-61420-5
  • Online ISBN 978-3-319-61421-2
  • Series Print ISSN 1613-5318
  • Series Online ISSN 2191-0812
  • Buy this book on publisher's site