Disorders of Blood Pressure Regulation

Phenotypes, Mechanisms, Therapeutic Options

  • Adel E. Berbari
  • Giuseppe Mancia

Table of contents

  1. Front Matter
    Pages i-xi
  2. General Aspects

    1. Front Matter
      Pages 1-1
    2. Stanley S. Franklin, Vanessa Bell, Gary F. Mitchell
      Pages 11-21
    3. Pietro Amedeo Modesti, Danilo Malandrino
      Pages 23-32
    4. Massimo Volpe, Carmine Savoia
      Pages 33-44
  3. Mechanisms of Hypertension Development

    1. Front Matter
      Pages 45-45
    2. Joey P. Granger, Frank T. Spradley
      Pages 47-66
    3. Gino Seravalle, Gianmaria Brambilla, Daniela Prata Pizzala, Guido Grassi
      Pages 67-79
    4. Sébastien Foulquier, Ludovit Paulis, Elena Kaschina, Pawel Namsolleck, Thomas Unger
      Pages 81-106
    5. Juan Carlos Yugar-Toledo, Ana Paula C. Faria, Heitor Moreno
      Pages 107-126
    6. Rosa Maria Bruno, Agostino Virdis, Stefano Taddei
      Pages 127-134
    7. Sandosh Padmanabhan, Li-En Tan, Anna F. Dominiczak
      Pages 135-154
  4. Hypertension Phenotypes: Monogenic Syndromes

    1. Front Matter
      Pages 155-155
    2. Hakan R. Toka
      Pages 157-175
    3. Katya De Groote, Laurent Demulier, Julie De Backer, Tine De Backer
      Pages 177-186
  5. Hypertension Phenotypes: The Heart

    1. Front Matter
      Pages 187-187
    2. Fabio Angeli, Gianpaolo Reboldi, Monica Trapasso, Adolfo Aita, Dario Turturiello, Paolo Verdecchia
      Pages 189-212
    3. Solomon Aronson
      Pages 213-221
    4. Daragh Finn, Colin J. McMahon
      Pages 223-231
    5. Harsimran S. Singh, Omar Kalim, Mark Osten, Lee N. Benson, Eric M. Horlick
      Pages 233-247
    6. S. Giannitsi, M. S. Kallistratos, L. E. Poulimenos, A. J. Manolis
      Pages 249-255
  6. Hypertension Phenotypes: The Central Nervous System and the Brain

    1. Front Matter
      Pages 257-257
    2. Gianfranco Parati, Carolina Lombardi, Krzysztof Narkiewicz, Jacek Wolf, Juan Eugenio Ochoa
      Pages 259-287
    3. Antoinette Marie Schoenthaler, Diana Margot Rosenthal
      Pages 289-305
  7. Hypertension Phenotypes: The Kidney

    1. Front Matter
      Pages 323-323
    2. Silvio Borrelli, Luca De Nicola, Giuseppe Conte, Roberto Minutolo
      Pages 325-339
    3. Attilio Losito
      Pages 341-350
    4. Adel E. Berbari, Najla A. Daouk, Giuseppe Mancia
      Pages 351-382
    5. Pantelis A. Sarafidis, Panagiotis Georgianos, Carmine Zoccali
      Pages 383-417
    6. Alexandre Persu, Patricia Van der Niepen
      Pages 419-443
    7. John D. Imig, Md. Abdul H. Khan, Ashraf El-Meanawy
      Pages 445-463
    8. Karen A. Griffin, Aaron J Polichnowski, Anil K. Bidani
      Pages 465-478
  8. Hypertension Phenotypes: Endocrine Causes

    1. Front Matter
      Pages 479-479
    2. Christian A. Koch
      Pages 481-512
    3. Nieves Martell-Claros, María Abad-Cardiel, Beatriz Alvarez-Alvarez, José A. García-Donaire
      Pages 513-524
    4. Graeme Eisenhofer, Jacques W. M. Lenders
      Pages 541-560
    5. V. Kotsis, C. Antza
      Pages 561-568
    6. Gian Paolo Rossi, Paul-Emmanuel Vanderriele
      Pages 569-584
  9. Special Types of Hypertension

    1. Front Matter
      Pages 585-585
    2. Cesare Cuspidi, Carla Sala, Marijana Tadic, Guido Grassi
      Pages 599-612
    3. Gino Seravalle, Guido Grassi, Giuseppe Mancia
      Pages 639-652
    4. Alena Shantsila, Gregory Y. H. Lip
      Pages 653-662
    5. Cesare Cuspidi, Carla Sala, Marijana Tadic, Guido Grassi
      Pages 663-673
    6. Andrew Smyth, Martin O’Donnell
      Pages 675-693
    7. Luke J. Laffin, George L. Bakris
      Pages 695-704

About this book


This book aims to present a comprehensive classification of hypertensive phenotypes based on underlying target organ involvement. Particular emphasis is placed on review and assessment of clinical presentation, pathophysiologic mechanisms, and possible specific therapeutic options for each hypertension phenotype. Several of these phenotypes are well known and well described in the literature, such as prehypertension, white coat and masked hypertension, isolated systolic hypertension, renovascular hypertension, endocrine hypertension, pediatric hypertension, and gestational hypertension. Other hypertension phenotypes, however, are not widely recognized, being reported only in special reviews; examples include hypertension associated with renal calculus disease and other rarer causes such as Turner syndrome, herbal and medicinal compounds, and pharmacologic agents. A detailed account of the various causes of monogenic hypertension is also included. Finally, a section is devoted to general aspects of hypertension, including the significance of blood pressure indices, the natural course of untreated and treated hypertension, hypertension mechanisms, genetics, and guidelines for blood pressure control. 


Prehypertension White coat and masked hypertension Isolated systolic hypertension Renovascular hypertension Endocrine hypertension Pediatric hypertension Gestational hypertension Monogenic hypertension Turner syndrome Renal calculus disease Mechanisms of hypertension

Editors and affiliations

  • Adel E. Berbari
    • 1
  • Giuseppe Mancia
    • 2
  1. 1.Internal MedicineAmerican University of Beirut Medical CenterBeirutLebanon
  2. 2.Emeritus Professor of MedicineUniversity of Milano-BicoccaMonzaItaly

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG 2018
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-59917-5
  • Online ISBN 978-3-319-59918-2
  • Series Print ISSN 2366-4606
  • Series Online ISSN 2366-4614
  • Buy this book on publisher's site