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DNA and Histone Methylation as Cancer Targets

  • Atsushi Kaneda
  • Yu-ichi Tsukada

Part of the Cancer Drug Discovery and Development book series (CDD&D)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Hengbin Wang, Jinrong Min, Trygve Tollefsbol
    Pages 1-15
  3. DNA Methylation and Cancer

    1. Front Matter
      Pages 17-17
    2. Isao Suetake, Mikio Watanebe, Kohei Takeshita, Saori Takahashi, Peter Carlton
      Pages 19-51
    3. Miao Shi, Li Shen
      Pages 53-73
    4. John P. Thomson, Richard R. Meehan
      Pages 75-96
    5. Joyce J. Thompson, Keith D. Robertson
      Pages 97-124
  4. Histone Methylation and Cancer

    1. Front Matter
      Pages 125-125
    2. Lidong Sun, Jia Fang
      Pages 127-150
    3. John R. Horton, Molly Gale, Qin Yan, Xiaodong Cheng
      Pages 151-219
    4. Wen Fong Ooi, Xiaosai Yao, Patrick Tan, Bin Tean Teh
      Pages 221-248
    5. Hiroaki Kato
      Pages 249-277
  5. DNA and Histone Methylation-Related Events Underlying Cancer

    1. Front Matter
      Pages 279-279
    2. Akira Kurozumi, Yusuke Goto, Atsushi Okato, Naohiko Seki
      Pages 281-296
    3. Ken Higashimoto, Keiichiro Joh, Hidenobu Soejima
      Pages 297-344
  6. DNA and Histone Methylation in Particular Types of Cancer

    1. Front Matter
      Pages 345-345
    2. Sung-Hun Lee, Young Zoon Kim
      Pages 347-376
    3. Keisuke Matsusaka, Atsushi Kaneda
      Pages 377-390
    4. Kimihito Cojin Kawabata, Toshio Kitamura
      Pages 391-401
    5. Sophia Mastoraki, Evi Lianidou
      Pages 403-436
    6. Eri Arai, Takuya Yotani, Yae Kanai
      Pages 437-460
    7. Hiromu Suzuki, Eiichiro Yamamoto, Hiroshi Nakase, Tamotsu Sugai
      Pages 461-487
  7. DNA and Histone Modifications in Diagnosis and Therapy of Cancer

    1. Front Matter
      Pages 531-531
    2. Masaki Kinehara, Yuki Yamamoto, Yoshitomo Shiroma, Mariko Ikuo, Akira Shimamoto, Hidetoshi Tahara
      Pages 533-584
    3. Takayoshi Suzuki
      Pages 585-604
  8. Future Directions

    1. Front Matter
      Pages 605-605
    2. Hideyuki Takeshima, Toshikazu Ushijima
      Pages 607-622

About this book

Introduction

This book will focus on DNA and histone methylation in epigenetics and describe how it is involved in the molecular mechanisms responsible for the development of cancer. Chapters will summarize the current knowledge of the molecular basis of DNA and histone methylation and explain how it is involved in cancer, describe the features of DNA and histone methylation associated with particular types of cancer, diagnostic/therapeutic applications, and future directions of DNA and histone methylation as cancer targets.

Keywords

Demethylation DNA Histone Hypermethylation Methylation

Editors and affiliations

  • Atsushi Kaneda
    • 1
  • Yu-ichi Tsukada
    • 2
  1. 1.Graduate School of MedicineChiba UniversityChibaJapan
  2. 2.Advanced Biological Information Research Division, INAMORI Frontier Research CenterKyushu UniversityFukuokaJapan

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-59786-7
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Humana Press, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-59784-3
  • Online ISBN 978-3-319-59786-7
  • Series Print ISSN 2196-9906
  • Series Online ISSN 2196-9914
  • Buy this book on publisher's site