Multiscale Mechanobiology of Bone Remodeling and Adaptation

  • Peter Pivonka

Part of the CISM International Centre for Mechanical Sciences book series (CISM, volume 578)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Peter Pivonka, Aaron Park, Mark R. Forwood
    Pages 1-60
  3. Justin Fernandez, Ju Zhang, Vickie Shim, Jacob T. Munro, Massimo Sartori, Thor Besier et al.
    Pages 123-174
  4. Taiji Adachi, Yoshitaka Kameo
    Pages 231-257

About this book


The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors.
Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.


Bone Remodeling Disease Systems Analysis Mechanobiology Multiscale Computational Modeling Musculoskeletal Modeling

Editors and affiliations

  • Peter Pivonka
    • 1
  1. 1.Biomedical Engineering & Spinal DisorderQueensland University of TechnologyBrisbaneAustralia

Bibliographic information

  • DOI
  • Copyright Information CISM International Centre for Mechanical Sciences 2018
  • Publisher Name Springer, Cham
  • eBook Packages Engineering Engineering (R0)
  • Print ISBN 978-3-319-58843-8
  • Online ISBN 978-3-319-58845-2
  • Series Print ISSN 0254-1971
  • Series Online ISSN 2309-3706
  • Buy this book on publisher's site