Cancer Neurology in Clinical Practice

Neurological Complications of Cancer and its Treatment

  • David Schiff
  • Isabel Arrillaga
  • Patrick Y. Wen

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Overview

    1. Front Matter
      Pages 1-1
    2. Andrew L. Lin, Lisa M. DeAngelis
      Pages 3-10
  3. Diagnostic Studies

    1. Front Matter
      Pages 11-11
    2. Raymond Huang, Patrick Y. Wen
      Pages 13-31
  4. Nervous System Involvement of Systemic Cancers

    1. Front Matter
      Pages 55-55
    2. Riccardo Soffietti, Federica Franchino, Roberta Rudà
      Pages 57-79
    3. Sophie Taillibert, Emilie Le Rhun, Marc C. Chamberlain
      Pages 81-111
    4. Gregory Davis, Michaela Lee, Dawit Aregawi, Mark E. Shaffrey, David Schiff, Jonathan H. Sherman
      Pages 113-125
  5. Neurological Complications of Cancer

    1. Front Matter
      Pages 141-141
    2. Surabhi Ranjan, David Schiff
      Pages 143-151
    3. Christa P. Benit, Melissa Kerkhof, Alberto Duran-Peña, Charles J. Vecht
      Pages 153-169
    4. Lisa R. Rogers
      Pages 171-191
    5. Matthew E. Shuman, Mark D. Johnson
      Pages 193-202
    6. Myrna R. Rosenfeld, Josep Dalmau
      Pages 221-238
  6. Neurological Complications of Cancer Therapy

    1. Front Matter
      Pages 239-239
    2. Damien Ricard, Thomas Durand, Arnault Tauziède-Espariat, Delphine Leclercq, Dimitri Psimaras
      Pages 241-273
    3. Craig A. Vargo, Leslie A. Ray, Herbert B. Newton
      Pages 275-310
    4. Deborah A. Forst, Patrick Y. Wen
      Pages 311-333
    5. Martha R. Neagu, Russell W. Jenkins, David Reardon
      Pages 335-344
    6. Eudocia Q. Lee, Patrick Y. Wen
      Pages 345-357
    7. Erin M. Dunbar, Yue Wang, Santosh Kesari
      Pages 359-376
  7. Neurological Complications of Specific Malignancies

    1. Front Matter
      Pages 397-397
    2. Justin T. Jordan, Thomas N. Byrne, Tracy Batchelor
      Pages 399-416
    3. Ming Chi, Manmeet S. Ahluwalia
      Pages 417-434
    4. Emilie Le Rhun, Sophie Taillibert, Marc C. Chamberlain
      Pages 435-469
    5. Rajiv Magge, Eli L. Diamond
      Pages 471-484
    6. Jennie W. Taylor
      Pages 485-495
    7. K. Ina Ly, Maciej M. Mrugala
      Pages 497-513
    8. Megan L. Kruse, David M. Peereboom
      Pages 515-526
    9. Sepideh Mokhtari, Thomas J. Kaley
      Pages 527-539
    10. Hamza Malek, Annise Wilson, Jeffrey Raizer
      Pages 541-557
    11. Joachim M. Baehring, Amy M. Chan
      Pages 559-569
    12. Lakshmi Nayak, Christian Grommes
      Pages 571-581
    13. Elie Naddaf, Michelle L. Mauermann
      Pages 583-595
    14. Elizabeth S. Duke, Scott L. Pomeroy, Nicole J. Ullrich
      Pages 597-614
  8. Neurological Complications in Long Term Cancer Survivors

    1. Front Matter
      Pages 615-615
  9. Back Matter
    Pages 627-643

About this book


This updated edition provides clinicians from various backgrounds and levels of training the information needed to optimally diagnose and manage neurologic complications of the nervous system.  Organized into seven sections, this comprehensive volume begins with an overview of diagnostic studies for neurologic complications involving the nervous system.  That is followed by sections on metastatic and non-metastatic complications of cancer involving the nervous system, and the interpretation, diagnosis, and management of common neuro-oncologic symptoms.  The next section reviews the neurologic complications of cancer therapy, including corticosteroids, radiation therapy, chemotherapy, targeted molecular therapies, immunotherapies, hematopoietic stem cell transplantation, and infections involving the nervous system.  The final section focuses on the most important neurologic complications in cancers arising from specific organs.  In addition to capturing the latest advancements in the rapidly evolving fields of oncology and cancer neurology, the goal of this resource is to lead clinicians toward prompt diagnosis and intervention in order to improve patient quality of life.

"This textbook is a valuable resource for medical oncologists and radiation oncologists, as well as neurologists and neuro-oncologists dealing with these patients. … Overall, the chapters are well organized, clearly written, fairly balanced, and reasonably up to date. … I would recommend it as a learning tool to physicians in training (medical students, residents, and fellows) and for more experienced physicians as both a review/ update and a way to gain more in-depth knowledge and insight into the neurologic problems of cancer patients." (John C. Flickinger, International Journal of Radiation Oncology Biology Physics, Vol. 73 (2), 2009)

 "The general organization of the book is logical and facilitates its practical and everyday use. … Overall this textbook is very comprehensive and encompasses main neuro-oncological challenges. … Schiff, Kesari and Wen have edited a very elegant and highly practical textbook, written by recognized authorities in their respective fields, which will be used by a wide range of medical and surgical specialists who are confronted on a daily basis with neurological manifestations of cancer in their practice." (I. Radovanovic and G. Zadeh, British Journal of Cancer, Vol. 100 (6), 2009)


EEG, EMG, Lumbar Puncture Neuro-Oncology, Neurological Disease in Cancer Systemic Cancers, Neurological Complications Therapy Complications, Specific Malignancies Complications complications of Therapies in Long Term Survivors

Editors and affiliations

  • David Schiff
    • 1
  • Isabel Arrillaga
    • 2
  • Patrick Y. Wen
    • 3
  1. 1.Harrison Distinguished Teaching, Professor of Neurology, Neurological Surgery, and MedicineUniversity of VirginiaCharlottesvilleUSA
  2. 2.Instructor, Harvard Medical SchoolMassachusetts General Hospital, Department of Neurology/Neuro-OncologyBostonUSA
  3. 3.Professor of Neurology, Harvard Medical SchoolDana-Farber/Brigham and Women’s Cancer Center, Center for Neuro-OncologyBostonUSA

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG 2018
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-57899-6
  • Online ISBN 978-3-319-57901-6
  • Buy this book on publisher's site