Endocannabinoids and Lipid Mediators in Brain Functions

  • Miriam┬áMelis

Table of contents

  1. Front Matter
    Pages i-xi
  2. Luigia Cristino, Roberta Imperatore, Letizia Palomba, Vincenzo Di Marzo
    Pages 1-26
  3. Anthony L. Berger, Angela M. Henricks, Matthew N. Hill, Ryan J. McLaughlin
    Pages 53-78
  4. Brady K. Atwood, David M. Lovinger
    Pages 109-153
  5. Andrew F. Scheyer, Henry G. S. Martin, Olivier J. Manzoni
    Pages 171-210
  6. Etienne Hebert-Chatelain, Giovanni Marsicano, Tifany Desprez
    Pages 211-235
  7. Sarah A. Laredo, William R. Marrs, Loren H. Parsons
    Pages 257-318

About this book


The science of cannabinoids is 50 years old. These past years provided a remarkable and constant number of breakthroughs, showing that the signaling mediated by endocannabinoids and lipid mediators impacts almost every function of the body. Indeed, this represents a special field of research, which allows tackling the complexity of biological functions, and provides potential therapeutic frameworks for a plethora of diseases. The number of exciting discoveries brought up to the scientific community almost on a daily basis highlights the importance of an updated volume on this topic. Particularly, given that potential therapeutic benefits of cannabis and cannabinoids are currently under heavy analysis in many Countries worldwide. Hence, the main objective of this book is to explore not only some of the many functions of endocannabinoids (and lipid mediators) in physiological control of networks at a cellular and molecular level, but also to extend this knowledge for potential use of cannabinoids and/or drugs regulating endocannabinoid levels in vivo as therapeutic target(s) in neurological and neuropsychiatric disorders. In this book new findings and ideas about the endocannabinoid system and its roles as neuronal circuit modulator related to human brain pathologies characterized by alterations in neuroplasticity will be highlighted. Endocannabinoid roles in key systems controlling appetite, pain, learning and memory, as well as sleep and stress responses will be presented. In addition, pathological processes associated with changes in endocannabinoid signaling will be discussed in the context of anxiety, autism, depression and addiction. This book will provide an excellent background to researchers looking for extending their areas of interest, and to newcomers in the field.


Endocannabinoids Lipid mediators Neural circuits Neuroplasticity Therapeutic benefits of cannabinoids

Editors and affiliations

  • Miriam┬áMelis
    • 1
  1. 1.Dept Biomedical Sciences, Division of Neuroscience and Clinical PharmacologyUniversity of CagliariCagliariItaly

Bibliographic information