Patient-specific Hemodynamic Computations: Application to Personalized Diagnosis of Cardiovascular Pathologies

  • Lucian Mihai Itu
  • Puneet Sharma
  • Constantin Suciu

Table of contents

  1. Front Matter
    Pages i-x
  2. Puneet Sharma, Lucian Itu, Constantin Suciu
    Pages 1-11
  3. Elisabeta Badila, Lucian Calmac, Diana Zamfir, Daniela Penes, Emma Weiss, Vlad Bataila
    Pages 13-59
  4. Tiziano Passerini, Lucian Itu, Puneet Sharma
    Pages 61-88
  5. Lucian Itu, Puneet Sharma, Tiziano Passerini, Ali Kamen, Constantin Suciu
    Pages 89-109
  6. Viorel Mihalef, Lucian Itu, Tommaso Mansi, Puneet Sharma
    Pages 111-152
  7. Constantin Suciu, Lucian Itu, Cosmin Nita, Anamaria Vizitiu, Iulian Stroia, Laszlo Lazăr et al.
    Pages 177-227

About this book


Hemodynamic computations represent a state-of-the-art approach for patient-specific assessment of cardiovascular pathologies. The book presents the development of reduced-order multiscale hemodynamic models for coronary artery disease, aortic coarctation and whole body circulation, which can be applied in routine clinical settings for personalized diagnosis. Specific parameter estimation frameworks are introduced for calibrating the parameters of the models and high performance computing solutions are employed to reduce their execution time. The personalized computational models are validated against patient-specific measurements.

The book is written for scientists in the field of biomedical engineering focusing on the cardiovascular system, as well as for research-oriented physicians in cardiology and industrial players in the field of healthcare technologies.


Aortic Coarctation Computational Modeling Coronary Artery Disease High Performance Computing Personalization Personalized Medicine

Editors and affiliations

  • Lucian Mihai Itu
    • 1
  • Puneet Sharma
    • 2
  • Constantin Suciu
    • 3
  1. 1.Transilvania University of Brasov BrasovRomania
  2. 2.Medical Imaging TechnologiesSiemens HealthcarePrincetonUSA
  3. 3.Siemens Corporate TechnologyBrasovRomania

Bibliographic information