Stroke Genetics

  • Pankaj Sharma
  • James F. Meschia

Table of contents

  1. Front Matter
    Pages i-xii
  2. Pankaj Sharma, James F. Meschia
    Pages 1-7
  3. Hugo J. Aparicio, Sudha Seshadri
    Pages 9-20
  4. Jane M. Maguire, Elizabeth G. Holliday, Christopher J. Oldmeadow, John Attia, Matthew P. A. Henderson, Guillaume Pare
    Pages 21-52
  5. Deena M. Nasr, Jennifer Fugate, Robert D. Brown Jr.
    Pages 53-78
  6. Alessandro Biffi, Jonathan Rosand
    Pages 79-92
  7. Lionel Ginsberg
    Pages 105-116
  8. Virginia W. Lin, Douglas M. Sproule, Michio Hirano, Steven G. Pavlakis
    Pages 117-134
  9. Hyacinth I. Hyacinth, Robert J. Adams
    Pages 135-161
  10. John W. Cole, Christopher A. Stack
    Pages 163-189
  11. Anne-Katrin Giese, Natalia S. Rost
    Pages 191-218
  12. Bradford B. Worrall, Nicole A. Chiota-McCollum, Andrew M. Southerland
    Pages 219-245
  13. Stéphanie Debette
    Pages 247-262
  14. Rainer Malik
    Pages 263-279
  15. Stacie L. Demel, Daniel Woo
    Pages 281-293
  16. José M. Ferro, Diana Aguiar de Sousa, Sofia Oliveira
    Pages 295-326
  17. Lauren E. Walker, Anna Stewart, Sir Munir Pirmohamed
    Pages 327-410
  18. Browne C. Lewis
    Pages 411-423
  19. Back Matter
    Pages 425-431

About this book

Introduction

This revised, expanded second edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genomewide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed.

Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.

Keywords

CADASIL Fabry GWAS MELAS cerebral hemorrhage genetics genome hypertension stem cell stroke

Editors and affiliations

  • Pankaj Sharma
    • 1
  • James F. Meschia
    • 2
  1. 1.Department of NeurologyInstitute of Cardiovascular Research Royal Holloway College, University of London Imperial College London Healthcare NHS TrustLondonUnited Kingdom
  2. 2.Department of NeurologyMayo ClinicJacksonvilleUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-56210-0
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-56208-7
  • Online ISBN 978-3-319-56210-0
  • About this book