Table of contents

  1. Front Matter
    Pages i-xxiv
  2. Patricia Khashayar
    Pages 1-15
  3. Patricia Khashayar
    Pages 17-51
  4. Patricia Khashayar
    Pages 53-82
  5. Patricia Khashayar
    Pages 95-125
  6. Patricia Khashayar
    Pages 153-175
  7. Patricia Khashayar
    Pages 177-190
  8. Patricia Khashayar
    Pages 191-193
  9. Back Matter
    Pages 195-197

About this book


This book addresses the important clinical problem of accurately diagnosing osteoporosis, and analyzes how Bone Turnover Markers (BTMs) can improve osteoporosis detection. In her research, the author integrated microfluidic technology with electrochemical sensing to embody a reaction/detection chamber to measure serum levels of different biomarkers, creating a microfluidic proteomic platform that can easily be translated into a biomarker diagnostic. The Osteokit System, a result of the integration of electrochemical system and microfluidic chips, is a unique design that offers the potential for greater sensitivity. The implementation, feasibility, and specificity of the Osteokit platform is demonstrated in this book, which is appropriate for researchers working on bone biology and mechanics, as well as clinicians.


Biomechanical sensors Bone biosensors Bone remodeling Electrochemistry Immunosensors Oc and CTX Biosensors Osteoporosis detection Point-of-Care testing Protein immobilization strategies Nanoprobe fabrication and validation

Authors and affiliations

  • Patricia¬†Khashayar
    • 1
  1. 1.Centre for Microsystems Technology (CMST), Faculty of Engineering and ArchitectureGhent UniversityGhentBelgium

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Springer, Cham
  • eBook Packages Engineering
  • Print ISBN 978-3-319-55052-7
  • Online ISBN 978-3-319-55053-4
  • Buy this book on publisher's site