Advertisement

Human Chromosome Atlas

Introduction to diagnostics of structural aberrations

  • Claudia Behrend
  • Javad Karimzad Hagh
  • Parvin Mehdipour
  • Gesa Schwanitz

Table of contents

  1. Front Matter
    Pages i-viii
  2. Claudia Behrend, Javad Karimzad Hagh, Parvin Mehdipour, Gesa Schwanitz
    Pages 1-1
  3. Claudia Behrend, Javad Karimzad Hagh, Parvin Mehdipour, Gesa Schwanitz
    Pages 3-9
  4. Claudia Behrend, Javad Karimzad Hagh, Parvin Mehdipour, Gesa Schwanitz
    Pages 11-13
  5. Claudia Behrend, Javad Karimzad Hagh, Parvin Mehdipour, Gesa Schwanitz
    Pages 15-196
  6. Claudia Behrend, Javad Karimzad Hagh, Parvin Mehdipour, Gesa Schwanitz
    Pages 197-203
  7. Claudia Behrend, Javad Karimzad Hagh, Parvin Mehdipour, Gesa Schwanitz
    Pages 205-205
  8. Back Matter
    Pages 207-207

About this book

Introduction

This atlas presents the results of cases of structural chromosome aberrations based on the currently available methods of analysis for different types of abnormality. It particularly focuses on which spectrum should be chosen when combining the different techniques to achieve the best method of diagnosis in individual cases, for example direct preparation of cells and mitoses, short or long-time cell culture, fluorescence in situ hybridization (FISH), analysis of interphases, microarray or DNA sequencing. Generally it has to be taken into account, that the development of new and improved investigation methods is forthcoming. Thus, by improvement of diagnostic possibilities new fields of investigation arise, and special groups of patients with cytogenetic analyses can be re-analysed under new research questions.

Keywords

Chromosome rearrangements Heteromorphisms Chromosome analyses by banding techniques FISH Genetic counselling

Authors and affiliations

  • Claudia Behrend
    • 1
  • Javad Karimzad Hagh
    • 2
  • Parvin Mehdipour
    • 3
  • Gesa Schwanitz
    • 4
  1. 1.Genetisch-diagnostisches LaborPraxis für Medizinische GenetikDüsseldorfGermany
  2. 2.Genetisch-diagnostisches LaborPraxis für Medizinische GenetikDüsseldorfGermany
  3. 3.Department of Medical GeneticsTehran University of Medical SciencesTehranIran
  4. 4.Biomedizinisches Zentrum, Institut für HumangenetikUniversitätsklinikum BonnGermany

Bibliographic information