Mediastinal Lesions

Diagnostic Pearls for Interpretation of Small Biopsies and Cytology

  • Anja C. Roden
  • Andre L. Moreira

Table of contents

  1. Front Matter
    Pages i-xii
  2. Frank Detterbeck
    Pages 1-3
  3. Robert J. Korst
    Pages 5-24
  4. Brett W. Carter, Edith M. Marom
    Pages 25-50
  5. Andre L. Moreira
    Pages 51-86
  6. Alexander Marx, Cleo-Aron Weis, Alexandar Tzankov, Philipp Ströbel
    Pages 87-148
  7. Anja C. Roden
    Pages 149-172
  8. Lucian R. Chirieac, Christopher A. French
    Pages 173-187
  9. Philipp Ströbel, Alexander Marx
    Pages 189-216
  10. Narasimhan P. Agaram
    Pages 233-255
  11. Andre L. Moreira, Anja C. Roden
    Pages 257-260
  12. Back Matter
    Pages 261-271

About this book


This book addresses the current concepts in tissue acquisition, diagnosis, and classification of mediastinal lesions in small biopsies including cytology. Examples of mediastinal diseases that are either more common, more challenging to diagnose, or have a differential diagnosis that is important and might require different modes of treatment are highlighted. The knowledge of some key morphologic features and immunohistochemical pitfalls will be helpful for the practicing pathologist to tackle this challenge. The general workup of a mediastinal biopsy and the workup of major disease groups in mediastinal pathology which the general pathologist should be familiar with is discussed. Morphologic and, if applicable, immunophenotypic and molecular features that can help to distinguish these disease entities are highlighted. Furthermore, the reader will learn about the pertinent clinical implications of the diseases. Mediastinal Lesions: Diagnostic Pearls for Interpretation of Small Biopsies and Cytology will be a reference guide for pathologists, pathologists-in-training, and allied professionals, including oncologists, pulmonologists, surgeons, and radiologists. 


Mediastinal cysts NUT midline carcinomas Non-neoplastic/inflammatory lesions Posterior mediastinum Thymic lesions

Editors and affiliations

  • Anja C. Roden
    • 1
  • Andre L. Moreira
    • 2
  1. 1.Department of PathologyMayo Clinic School of MedicineRochesterUSA
  2. 2.Department of PathologyNew York University Langone Medical CenterNew YorkUSA

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-48377-1
  • Online ISBN 978-3-319-48379-5
  • Buy this book on publisher's site