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Immunotherapy of Melanoma

  • Anand Rotte
  • Madhuri Bhandaru

Table of contents

  1. Front Matter
    Pages i-xi
  2. Melanoma

    1. Front Matter
      Pages 1-1
    2. Anand Rotte, Madhuri Bhandaru
      Pages 3-20
    3. Anand Rotte, Madhuri Bhandaru
      Pages 21-47
    4. Anand Rotte, Madhuri Bhandaru
      Pages 49-77
    5. Anand Rotte, Madhuri Bhandaru
      Pages 79-109
  3. Tumor Immunology

    1. Front Matter
      Pages 111-111
    2. Anand Rotte, Madhuri Bhandaru
      Pages 113-142
    3. Anand Rotte, Madhuri Bhandaru
      Pages 143-166
    4. Anand Rotte, Madhuri Bhandaru
      Pages 167-198
    5. Anand Rotte, Madhuri Bhandaru
      Pages 199-232
  4. Immune Based Drugs Approved for Treatment of Melanoma

    1. Front Matter
      Pages 233-233
    2. Anand Rotte, Madhuri Bhandaru
      Pages 235-256
    3. Anand Rotte, Madhuri Bhandaru
      Pages 257-273
    4. Anand Rotte, Madhuri Bhandaru
      Pages 275-296
    5. Anand Rotte, Madhuri Bhandaru
      Pages 297-317
    6. Anand Rotte, Madhuri Bhandaru
      Pages 319-332
    7. Anand Rotte, Madhuri Bhandaru
      Pages 333-347
  5. Ongoing Research

    1. Front Matter
      Pages 349-349
    2. Anand Rotte, Madhuri Bhandaru
      Pages 351-416
  6. Challenges

    1. Front Matter
      Pages 417-417
    2. Anand Rotte, Madhuri Bhandaru
      Pages 419-434

About this book

Introduction

This book focusses on the different types of immunotherapeutics that are currently being used and developed for the treatment of melanoma. In recent years, immunotherapy has revolutionized the treatment of metastatic melanoma and other types of cancer.

Discussing treatment options for melanoma and the success of immunotherapy along with the challenges of immunotherapy, this book covers epidemiology, susceptibility genes, and treatment recommendations from Society for Immunotherapy of Cancer, as well as immune based therapies such as aldesleukin, Intron-A, Sylatron, Yervoy, Opdivo, Keytruda, Imlygic, DC vaccines and adoptive cell therapy.

The detailed information included on the key immune cells involved in anti-tumor immune response and immune-inhibitory mechanisms in tumor microenvironment will aid the understanding of tumor immunology. Both academic as well as industry-based researchers, developing novel anti-cancer therapies, will also benefit from the details of promising molecular targets and immunotherapeutic strategies under investigation.

With 132 illustrations including synopsis tables for important information, over 1200 references (majority of which are openly accessible) and details of more than 150 ongoing clinical trials, this book is a valuable source of information for health care providers as well as cancer biologists interested in learning about melanoma and the significant advances made by immunotherapy. 

Keywords

Melanoma Immunotherapy Check point blockers Cancer vaccines Adoptive cell therapy

Authors and affiliations

  • Anand Rotte
    • 1
  • Madhuri Bhandaru
    • 2
  1. 1.Dermatology & Skin Science, Faculty of MedicineUniversity of British ColumbiaVancouverCanada
  2. 2.Dermatology & Skin Science, Faculty of MedicineUniversity of British Columbia VancouverCanada

Bibliographic information