Modelling the Toxicity of Nanoparticles

  • Lang Tran
  • Miguel A. Bañares
  • Robert Rallo

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 947)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Characterisation

    1. Front Matter
      Pages 1-1
  3. Exposure

    1. Front Matter
      Pages 25-25
    2. Araceli Sánchez Jiménez, Martie van Tongeren
      Pages 27-40
    3. David González-Gálvez, Gemma Janer, Gemma Vilar, Alejandro Vílchez, Socorro Vázquez-Campos
      Pages 41-69
    4. Uschi M. Graham, Gary Jacobs, Robert A. Yokel, Burtron H. Davis, Alan K. Dozier, M. Eileen Birch et al.
      Pages 71-100
  4. Modelling

    1. Front Matter
      Pages 101-101
    2. Ceyda Oksel, Cai Y. Ma, Jing J. Liu, Terry Wilkins, Xue Z. Wang
      Pages 103-142
    3. Christian Riebeling, Harald Jungnickel, Andreas Luch, Andrea Haase
      Pages 143-171
    4. Hender Lopez, Erik G. Brandt, Alexander Mirzoev, Dmitry Zhurkin, Alexander Lyubartsev, Vladimir Lobaskin
      Pages 173-206
  5. Case Studies

    1. Front Matter
      Pages 255-255
    2. Martin Brehm, Alexander Kafka, Markus Bamler, Ralph Kühne, Gerrit Schüürmann, Lauri Sikk et al.
      Pages 257-301
    3. Andrea-Nicole Richarz, Aggelos Avramopoulos, Emilio Benfenati, Agnieszka Gajewicz, Nazanin Golbamaki Bakhtyari, Georgios Leonis et al.
      Pages 303-324
    4. Hanne Vriens, Dominik Mertens, Renaud Regret, Pinpin Lin, Jean-Pierre Locquet, Peter Hoet
      Pages 325-344
  6. Back Matter
    Pages 345-352

About this book

Introduction

In today’s nanotechnology and pharmaceutical research, alternative toxicology testing methods are crucial for ethically and commercially sound practice. This book provides practical guidelines on how to develop and validate quantitative nanostructure-toxicity relationship (QNTR) models, which are ideal for rapidly exploring the effects of a large number of variables in complex scenarios.

Through contributions by academic, industrial, and governmental experts, Modelling the Toxicity of Nanoparticles delivers clear instruction on these methods and their integration and use in risk assessment. Specific topics include the physico-chemical characteristics of engineered nanoparticles, nanoparticle interactions, in vivo nanoparticle processing, and more.

A much-needed practical guide, Modelling the Toxicity of Nanoparticles is a key text for researchers as well as government and industry regulators.

Keywords

Engineereed nanomaterials Exposure Modeling toxicity Predicting toxicity QNTR Risk assessment

Editors and affiliations

  • Lang Tran
    • 1
  • Miguel A. Bañares
    • 2
  • Robert Rallo
    • 3
  1. 1.Institute of Occupational MedicineEdinburghUnited Kingdom
  2. 2.Institute of Catalysis & Petrochemistry, CSICMadridSpain
  3. 3.Universitat Rovira i VirgiliDepartament d’Enginyeria Informatica i MatematiquesTarragonaSpain

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-47754-1
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-47752-7
  • Online ISBN 978-3-319-47754-1
  • Series Print ISSN 0065-2598
  • Series Online ISSN 2214-8019
  • About this book