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Advances in Understanding Kingella kingae

  • Joseph W.  St. Geme, III

Part of the SpringerBriefs in Immunology book series (BRIEFSIMMUN)

Table of contents

  1. Front Matter
    Pages i-vii
  2. Stéphane Bonacorsi, Philippe Bidet, Pablo Yagupsky
    Pages 1-12
  3. Eric A. Porsch, Katherine A. Rempe
    Pages 29-40
  4. Eric A. Porsch, Kevin J. Downes
    Pages 41-47
  5. Gunnar Kahlmeter, Erika Matuschek, Pablo Yagupsky
    Pages 65-72
  6. Pablo Yagupsky, Nataliya Balashova
    Pages 73-83
  7. Vanessa L. Muñoz, Kimberly F. Starr, Eric A. Porsch
    Pages 85-97

About this book

Introduction

This book describes the growing body of information on the epidemiology, clinical manifestations, transmission, pathogenesis, diagnosis, and treatment of Kingella kingae infections in young children. In addition, it covers experimental methods that have been developed to study the microbiology, genetics, and virulence factors of K. kingae, information that provides the foundation for new approaches to treatment and prevention of K. kingae disease. With this content in mind, excerpts from the book will be of relevance for clinicians who care for pediatric patients, for clinical microbiologists who are involved in detecting organisms in clinical specimens, and for scientists who are studying K. kingae in an effort to develop novel targets for antimicrobial therapy and new approaches to prevention.

First isolated in the 1960s by Elizabeth O. King, a bacteriologist at the CDC, Kingella kingae was largely ignored over the next two decades as a human pathogen because of its uncommon recovery from patients with disease. However, in recent years K. kingae has been increasingly recognized as a clinically important pathogen in young children, and is currently recognized as the leading cause of osteoarticular infections in young children in a growing number of countries. Research into this organism has grown tremendously over the past 15 years, resulting in a better appreciation of the importance of K. kingae in pediatric patients and of the molecular mechanisms of disease. 

Keywords

Kingella kingae microbiology infection pathogenesis treatment prevention

Editors and affiliations

  • Joseph W.  St. Geme, III
    • 1
  1. 1.Physician-in-ChiefThe Children's Hospital of PhiladelphiaPhiladelphiaUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-43729-3
  • Copyright Information The Author(s) 2016
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-43728-6
  • Online ISBN 978-3-319-43729-3
  • Series Print ISSN 2194-2773
  • Series Online ISSN 2194-2781
  • Buy this book on publisher's site