Skin Stress Response Pathways

Environmental Factors and Molecular Opportunities

  • Georg T. Wondrak

Table of contents

  1. Front Matter
    Pages i-ix
  2. Risa Tamagawa-Mineoka, Mayumi Ueta, Norito Katoh
    Pages 235-249
  3. Back Matter
    Pages 449-457

About this book


It is now established that the interplay between environmental exposure and molecular stress response pathways plays a critical role in skin health and disease, and a refined mechanistic understanding of this phenomenon at the molecular level promises to open new avenues for targeted therapeutic strategies that may benefit patients in the near future. Coauthored by recognized international leaders in molecular and clinical biomedical sciences, this novel book provides a comprehensive perspective on environmental exposure-induced skin stress response pathways. Focusing on molecular opportunities targeting skin stress response pathways that are involved in cutaneous barrier function and repair, antimicrobial defense, immune regulation, inflammation, and malignant progression, the book is essential reading for students, basic researchers, and biomedical health care professionals interested in skin health and disease with implications for small molecule therapeutic development.


skin barrier function skin health environmental exposure stress response signaling small molecule intervention strengthening skin function

Editors and affiliations

  • Georg T. Wondrak
    • 1
  1. 1.Department of Pharmacology and ToxicologyCollege of Pharmacy & The University of Arizona Cancer Center, Department of Pharmacology and ToxicologyTUCSONUSA

Bibliographic information