In Vitro Fertilization

A Textbook of Current and Emerging Methods and Devices

  • Zsolt Peter Nagy
  • Alex C. Varghese
  • Ashok Agarwal

Table of contents

  1. Embryo Evaluation, Grading, and Assisted Hatching

    1. Manesh Kumar Panner Selvam, Damayanthi Durairajanayagam, Ashok Agarwal
      Pages 535-547
    2. Christine Leary, Danielle G. Smith, Henry J. Leese, Roger G. Sturmey
      Pages 549-556
    3. David K. Gardner, Philipp Reineck, Brant C. Gibson, Jeremy G. Thompson
      Pages 557-566
    4. Matteo A. Avella, Kristine A. Milne, Shagufta Dawood, Adam Dawood, Michael J. Tucker
      Pages 567-579
  2. Biopsy Procedures on Oocytes and Embryos

    1. Front Matter
      Pages 581-581
    2. Markus Montag
      Pages 583-590
    3. Alan R. Thornhill
      Pages 591-601
    4. Sarthak Sawarkar, Santiago Munné
      Pages 603-612
    5. Steven J. McArthur, Don Leigh, Maria Traversa, James Marshall, Robert P. S. Jansen
      Pages 613-621
  3. Cryopreservation

    1. Front Matter
      Pages 623-623
    2. Ana D. Martins, Ashok Agarwal, Ralf Henkel
      Pages 625-642
    3. Vladimir Isachenko, Gohar Rahimi, Peter Mallmann, Raul Sanchez, Evgenia Isachenko
      Pages 643-654
    4. Giovanni Coticchio, Lucia De Santis
      Pages 655-664
    5. Liesl Nel-Themaat, Ching-Chien Chang, Thomas Elliott, Diana P. Bernal, Graham Wright, Zsolt Peter Nagy
      Pages 689-700
    6. Juergen Liebermann
      Pages 701-712
    7. Pasquale Patrizio, Sherman Silber
      Pages 713-720
    8. Kathryn J. Go, Paula Dwan, Linda Hillis
      Pages 721-726
  4. Embryo Transfer and Advanced Treatment Options

    1. Front Matter
      Pages 727-727
    2. Thorir Hardarson, Matts Wikland
      Pages 729-733
    3. Jutimala Bhattacharyya, Sankalp Singh, Madhab C. Das, Kanna Jayaprakasan
      Pages 735-749
    4. Bruce S. Shapiro, Forest C. Garner, Martha Aguirre
      Pages 765-778
  5. Management and Regulation in the ART Laboratory

    1. Front Matter
      Pages 779-779
    2. Jacques Cohen, Stephen Fiser, Giles Tomkin
      Pages 781-785
    3. Doris J. Baker
      Pages 787-800
    4. Rachel Cutting
      Pages 801-805
    5. Julius Hreinsson, Borut Kovačič
      Pages 807-817
    6. Fabiola C. Bento, Sandro C. Esteves
      Pages 819-822
    7. James Stanger
      Pages 823-832
  6. Innovations, Risks and Safety in ART

    1. Front Matter
      Pages 845-845
    2. Alex C. Varghese, Charalampos S. Siristatidis
      Pages 847-860
    3. Josef Fulka Jr, Helena Fulka
      Pages 869-875
    4. Tom Beckitt, Tammie Roy
      Pages 891-894
  7. Molecular Reproduction

  8. Back Matter
    Pages 945-962

About this book


Now in its revised and expanded second edition - including over 20 new chapters - this comprehensive textbook remains a unique and accessible description of the current and developing diagnostic and treatment techniques and technologies comprising in vitro fertilization (IVF). Arranged thematically in sections, each chapter covers a key topic in IVF in a sensible presentation. Parts one and two describe the planning, design and organization of an ART unit and IVF laboratory and equipment and systems, respectively. The sections that follow provide detailed descriptions of IVF techniques, embryo culture methods, sperm processing and selection, insemination procedures, micromanipulation, embryo evaluation, cryopreservation, and embryo transfer. Concluding sections address issues of management and regulation of ART labs across the globe, as well as special topics and emerging techniques and devices. Chapter authors, all experts in the field, contribute their expertise from around the world.

With the addition of learning key points and review questions at the beginning and end of each chapter, this new edition of In Vitro Fertilization is a readily accessible, high quality instructional resource for reproductive medicine trainees at all levels. Practicing reproductive endocrinologists, urologists, and embryologists also will find value in the book, as will infertility researchers.


ART unit Assisted hatching Assisted reproductive technology (ART) Blastocyst Cryopreservation Egg banking Embryo Embryo transfer Fertility preservation Gamete Infertility Intracytoplasmic sperm injection (ICSI) In vitro fertilization (IVF) In vitro maturation (IVM) Microfluidics Micromanipulation Oocyte Sperm Sperm selection Vitrification

Editors and affiliations

  • Zsolt Peter Nagy
    • 1
  • Alex C. Varghese
    • 2
  • Ashok Agarwal
    • 3
  1. 1.Reproductive Biology Associates – PreludeAtlantaUSA
  2. 2.Astra Fertility GroupMississaugaCanada
  3. 3.Cleveland ClinicClevelandUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Switzerland AG 2019
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-43010-2
  • Online ISBN 978-3-319-43011-9
  • Buy this book on publisher's site