Gastrointestinal Stromal Tumors

Bench to Bedside

  • Charles R. Scoggins
  • Chandrajit P. Raut
  • John T. Mullen

Table of contents

  1. Front Matter
    Pages i-xi
  2. Christina L. Roland, Barry W. Feig
    Pages 1-5
  3. Taylor M. Coe, Jason K. Sicklick
    Pages 7-15
  4. Katherine A. Janeway
    Pages 45-57
  5. Localized Disease

    1. Front Matter
      Pages 59-59
    2. Osman Yuksel, William R. Brugge
      Pages 91-102
    3. Kavitha M. Nair, Field F. Willingham
      Pages 103-115
    4. Jack W. Rostas, Prejesh Philips
      Pages 117-128
    5. Tiffany C. Cox, Vedra A. Augenstein, Sam Schell, B. Todd Heniford
      Pages 129-144
    6. W. W. Tseng, S. Chopra, E. Jung, B. L. Eisenberg
      Pages 145-154
  6. Advanced Disease

    1. Front Matter
      Pages 155-155
    2. Christian F. Meyer
      Pages 157-170
    3. Gabriel Tinoco, Guozhi Hu, Ana Paz-Mejía, Jonathan Trent
      Pages 171-185
    4. David A. Mahvi, Emily Z. Keung, Chandrajit P. Raut
      Pages 187-208
    5. Andrew D. Morris, Shishir K. Maithel, David A. Kooby
      Pages 209-223
    6. Brittany A. Potz, Thomas J. Miner
      Pages 225-239
  7. Back Matter
    Pages 241-243

About this book


This textbook provides a comprehensive, state of the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in GIST. The book  reviews new data about risk factors for the disease, profiles the new staging system for GIST, highlights our current understanding of genetic mutations that lead to GIST, and provides new perspectives about imaging of GIST tumors. For localized disease, a greater appreciation of organ-sparing approaches and the importance of preservation of gastrointestinal function is discussed in detail, and advances in surgical techniques are highlighted, including minimally invasive surgery. For metastatic disease, the molecular biology of GIST is reviewed in a detailed and understandable manner, including the data that has fostered novel targeted approaches that have revolutionized management. Several landmark trials have been published in the last few years and are placed in context with respect to current management. Integration of surgery and systemic therapy through consolidative approaches has yielded provocative data that promises to further advance the field, and major advances in this domain are also discussed. Gastrointestinal Stromal Tumors: Bench to Bedside will serve as a very useful resource for physicians and researchers dealing with, and interested in, this challenging malignancy. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.


Endoscopic evaluation GIST Liver resection Neoadjuvant Rx multivisceral resections

Editors and affiliations

  • Charles R. Scoggins
    • 1
  • Chandrajit P. Raut
    • 2
  • John T. Mullen
    • 3
  1. 1.School of MedicineUniversity of LouisvilleLouisvilleUSA
  2. 2.Brigham & Women’s HospitalHarvard Medical SchoolBostonUSA
  3. 3.Harvard Medical SchoolBostonUSA

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2017
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-319-42630-3
  • Online ISBN 978-3-319-42632-7
  • Buy this book on publisher's site