Small Animal Imaging

Basics and Practical Guide

  • Fabian Kiessling
  • Bernd J. Pichler
  • Peter Hauff

Table of contents

  1. Front Matter
    Pages i-xix
  2. Role of Small Animal Imaging

    1. Front Matter
      Pages 1-1
    2. Sally-Ann Emmas, Paul D. Hockings, John C. Waterton
      Pages 33-46
    3. David Stout
      Pages 47-67
    4. Nicolau Beckmann, Birgit Ledermann
      Pages 69-87
  3. Study Planning and Animal Preparation

    1. Front Matter
      Pages 89-89
    2. Hannes-Friedrich Ulbrich
      Pages 101-116
    3. Marc Hein, Anna B. Roehl, René H. Tolba
      Pages 117-126
    4. Peter Hauff, Klaus Nebendahl
      Pages 127-152
  4. Imaging Modalities and Probes

    1. Front Matter
      Pages 153-153
    2. Fabian Kiessling, Bernd Pichler, Peter Hauff
      Pages 155-161
    3. Norman Koglin, Andre Mueller, Andrew W. Stephens, Ludger M. Dinkelborg
      Pages 163-176
    4. Igor Jacobs, Gustav J. Strijkers, Henk M. Keizer, Henk M. Janssen, Hisataka Kobayashi, Klaas Nicolay
      Pages 177-200
    5. Robert Brauweiler, Klaus Engelke, Martin Hupfer, Willi A. Kalender, Marek Karolczak, Hubertus Pietsch
      Pages 201-225
    6. MRI
      Aileen Schroeter, Markus Rudin, Eliana Gianolio, Alessandra Viale, Daniela Delli Castelli, Silvio Aime et al.
      Pages 227-324
    7. Stuart Foster, J. M. Hyvelin, Minalini Lakshman, Andrew Needles, I. Tardy, François Tranquart
      Pages 325-360
    8. Clemens Decristoforo, Uwe Haberkorn, Roland Haubner, Walter Mier, Sibylle I. Ziegler
      Pages 361-402
    9. Frauke Alves, Julia Bode, Peter Cimalla, Ingrid Hilger, Martin Hofmann, Volker Jaedicke et al.
      Pages 403-490
    10. Hans F. Wehrl, Mario Amend, André Thielcke
      Pages 491-507
  5. Ex Vivo Validation Methods

  6. Data Postprocessing

    1. Front Matter
      Pages 527-527
    2. Felix Gremse
      Pages 529-545
    3. Martin S. Judenhofer, Stefan Wiehr, Damaris Kukuk, Kristina Fischer, Bernd J. Pichler
      Pages 547-557
    4. J. van den Hoff
      Pages 559-580
  7. Special Applications

    1. Front Matter
      Pages 591-591
    2. Laura C. Rose, Jeff W. M. Bulte
      Pages 593-603
    3. M. Brom, W. A. Eter, I. van der Kroon, S. M. A. Willekens, A. Eek, M. Boss et al.
      Pages 605-625
    4. Katrien Vandoorne, Tal Raz, Stav Sapoznik, Inbal E. Biton, Joel R. Garbow, Michal Neeman
      Pages 627-650
    5. Matthias W. Laschke, Michael D. Menger
      Pages 651-662
    6. Michael Schäfers, Michael Kuhlmann, Lars Stegger, Klaus Schäfers, Sven Hermann
      Pages 663-688
    7. Yannic Waerzeggers, Bastian Zinnhardt, Alexandra Winkeler, Parisa Monfared, Sonja Schelhaas, Thomas Viel et al.
      Pages 689-725
    8. J. Hamaide, L. Van Ruijssevelt, F. Kara, G. De Groof, A. Van der Linden
      Pages 727-760
    9. Heike Endepols, Bernd Neumaier
      Pages 761-772
    10. Wolfgang A. Weber, Fabian Kiessling
      Pages 793-819
    11. Melissa N. McCracken, Owen N. Witte
      Pages 821-844
    12. Anna-Maria Rolle, Stefan Wiehr
      Pages 845-856
  8. Back Matter
    Pages 857-875

About this book


This textbook is a practical guide to the use of small animal imaging in preclinical research that will assist in the choice of imaging modality and contrast agent and in study design, experimental setup, and data evaluation. All established imaging modalities are discussed in detail, with the assistance of numerous informative illustrations. While the focus of the new edition remains on practical basics, it has been updated to encompass a variety of emerging imaging modalities, methods, and applications. Additional useful hints are also supplied on the installation of a small animal unit, study planning, animal handling, and cost-effective performance of small animal imaging. Cross-calibration methods and data postprocessing are considered in depth. This new edition of Small Animal Imaging will be an invaluable aid for researchers, students, and technicians involved in research into and applications of small animal imaging.


Preclinical Research Non invasive Imaging in Animals MR contrast agents Animal anesthesia Established imaging modalities Cost-effective imaging Identifying Biomarkers Diagnostic probe design

Editors and affiliations

  • Fabian Kiessling
    • 1
  • Bernd J. Pichler
    • 2
  • Peter Hauff
    • 3
  1. 1.Universitätsklinikum AachenAachenGermany
  2. 2.Universitätsklinikum TübingenTübingenGermany
  3. 3.Bayer AG, Drug Discovery PharmaceuticalsBerlinGermany

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-319-42200-8
  • Online ISBN 978-3-319-42202-2
  • Buy this book on publisher's site