Non-coding RNAs in Colorectal Cancer

  • Ondrej Slaby
  • George A. Calin

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 937)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Non-coding RNAs: Biology and Implications in Colorectal Cancer Pathogenesis

    1. Front Matter
      Pages 1-1
    2. Sonja Hombach, Markus Kretz
      Pages 3-17
    3. Yinxue Yang, Yong Du, Xiaoming Liu, William C. Cho
      Pages 19-51
    4. Claire Josse, Vincent Bours
      Pages 53-69
    5. Daniele Fanale, Nadia Barraco, Angela Listì, Viviana Bazan, Antonio Russo
      Pages 93-108
    6. Sippy Kaur, Johanna E. Lotsari-Salomaa, Riitta Seppänen-Kaijansinkko, Päivi Peltomäki
      Pages 109-122
    7. Pavel Vodicka, Barbara Pardini, Veronika Vymetalkova, Alessio Naccarati
      Pages 123-149
  3. Non-coding RNAs: New Class of Biomarkers in Colorectal Cancer

    1. Front Matter
      Pages 151-151
    2. Manuela Ferracin, Laura Lupini, Alessandra Mangolini, Massimo Negrini
      Pages 171-181
  4. Non-coding RNAs: Therapeutic Targets and Colorectal Cancer Therapeutics

    1. Front Matter
      Pages 205-205
    2. Daniele Fanale, Marta Castiglia, Viviana Bazan, Antonio Russo
      Pages 207-228
    3. Hirofumi Yamamoto, Masaki Mori
      Pages 239-247
  5. Back Matter
    Pages 249-252

About this book


This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles played by non-coding RNAs in molecular hallmarks of colorectal cancer.

This work further provides the comprehensive overview and novel insights into using of non-coding RNAs as colorectal cancer biomarkers enabling early detection of the disease, prognostic stratification of the patients and prediction of therapeutic response.

The reader is introduced to the overview of modern non-coding RNAs-based therapeutic strategies, and summary of their preclinical testing performed in colorectal cancer. The work is written for researchers who want to explore current state of the knowledge in this interesting field of molecular oncology. 


Non-coding RNAs biomarkers colorectal cancer long non-coding RNAs microRNAs pathogenesis therapy

Editors and affiliations

  • Ondrej Slaby
    • 1
  • George A. Calin
    • 2
  1. 1.Central European Institute of TechnologyMasaryk UniversityBrnoCzech Republic
  2. 2.Department of Experimental Therapeutics Division of Cancer MedicineThe University of Texas MD Anderson Cancer CenterHouston, TXUSA

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-42057-8
  • Online ISBN 978-3-319-42059-2
  • Series Print ISSN 0065-2598
  • Series Online ISSN 2214-8019
  • Buy this book on publisher's site