Basic Science of PET Imaging

  • Magdy M.¬†Khalil

Table of contents

  1. Front Matter
    Pages i-xix
  2. Physics, Radiation Safety and Dosimetry of PET

    1. Front Matter
      Pages 1-1
    2. Taher Hosny, Eman Al-Anezi, Magdy M. Khalil
      Pages 3-35
    3. Debbie Peet, Sue Edyvean
      Pages 37-64
    4. Michael G. Stabin
      Pages 65-76
  3. PET Chemistry and Regulation of PET Radiopharmaceuticals

    1. Front Matter
      Pages 77-77
    2. Stefano Boschi, Filippo Lodi
      Pages 79-103
    3. Filippo Lodi, Stefano Boschi
      Pages 105-126
    4. James R. Ballinger, Jacek Koziorowski
      Pages 127-143
  4. PET Physics and Instrumentation

    1. Front Matter
      Pages 171-171
    2. Srilalan Krishnamoorthy, Jeffrey P. Schmall, Suleman Surti
      Pages 173-197
    3. Magdy M. Khalil
      Pages 199-228
  5. PET Image Reconstruction, Processing and Quantitation

    1. Front Matter
      Pages 257-257
    2. Magdy M. Khalil
      Pages 303-322
    3. Hiroshi Watabe
      Pages 323-352
  6. PET Imaging Artifacts and Correction Techniques

    1. Front Matter
      Pages 353-353
    2. Kjell Erlandsson
      Pages 355-378
  7. Scientific and Clinical Basis of PET Applications

    1. Front Matter
      Pages 397-397
    2. Abhishek Mahajan, Gary Cook
      Pages 399-427
    3. Abhishek Mahajan, Gary Cook
      Pages 429-450
    4. Ran Klein, Robert A. deKemp
      Pages 451-483
    5. Joe Barfett, Reza Vali, Amer Shammas
      Pages 537-575
    6. Maria Picchio, Elena Incerti, Nadia Di Muzio
      Pages 577-608
  8. Back Matter
    Pages 609-619

About this book


This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and
its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.


Hybrid Imaging Molecular Imaging Motion Correction in PET PET Data Analysis PET Kinetics PET Physics and Instrumentation PET Radiopharmaceuticals PET Radiopharmacy PET/CT Quantitative PET Imaging: Radiation Dosimetry of PET imaging

Editors and affiliations

  • Magdy M.¬†Khalil
    • 1
  1. 1.Medical Biophysics Department of Physics Faculty of ScienceHelwan UniversityCairoEgypt

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2017
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-319-40068-6
  • Online ISBN 978-3-319-40070-9
  • Buy this book on publisher's site