Molecular and Cellular Biology of Platelet Formation

Implications in Health and Disease

  • Harald Schulze
  • Joseph Italiano

Table of contents

  1. Front Matter
    Pages i-x
  2. Megakaryocytes and Thrombopoiesis

    1. Front Matter
      Pages 1-1
    2. Joseph E. Italiano Jr.
      Pages 3-22
    3. Harald Schulze, Daniela Semeniak, Alessandra Balduini
      Pages 93-114
    4. Matthew T. Rondina, Hansjörg Schwertz
      Pages 115-129
  3. Platelet Biology: Signals and Functions

    1. Front Matter
      Pages 131-131
    2. Robert Flaumenhaft, Secil Koseoglu
      Pages 133-152
    3. Alexandra Mazharian, Yotis A. Senis
      Pages 153-173
    4. Wolfgang Bergmeier, Ellen C. O’Shaughnessy
      Pages 175-191
    5. Amanda E. Au, Marion Lebois, Irina Pleines, Emma C. Josefsson
      Pages 193-220
    6. Rick Kapur, John W. Semple
      Pages 221-237
    7. Markus Bender, Bernhard Nieswandt
      Pages 239-263
  4. Platelets in Health and Disease

    1. Front Matter
      Pages 265-265
    2. Christof Dame, Viola Lorenz, Martha Sola-Visner
      Pages 267-291
    3. Deya Cherpokova, Bernhard Nieswandt
      Pages 293-306
    4. Tamam Bakchoul, Andreas Greinacher
      Pages 327-349
    5. Günther Schönrich, Martin J. Raftery
      Pages 351-362
    6. Tamam Bakchoul, Harald Schulze
      Pages 363-379
  5. Future Perspectives for Platelet Biogenesis

    1. Front Matter
      Pages 381-381
    2. Christian J. Braun, Christoph Klein
      Pages 383-398
    3. Peter Karagiannis, Hiroshi Endo, Koji Eto
      Pages 399-420
    4. Lisette Johana Latorre Rey, Ute Modlich
      Pages 421-460

About this book


This book gives a comprehensive insight into platelet biogenesis, platelet signal transduction, involvement of platelets in disease, the use of diverse animal models for platelet research and future perspectives in regard to platelet production and gene therapy. Being  written by international experts, the book is a concise state-of-the art work in the field of platelet biogenesis, biology and research. It represents an indispensable tool for research scientists in biomedicine, vascular biology, hematopoiesis and hemostasis and specifically for scientists in platelet research, as well as for clinicians in the field of hematology and transfusion medicine.​



Animal Models Hematopoiesis Megakaryocytes, Megakaryopoiesis Platelet related disorders Platelets Thrombosis

Editors and affiliations

  • Harald Schulze
    • 1
  • Joseph Italiano
    • 2
  1. 1.Institute of Experimental Biomedicine IUniversity Hospital WürzburgWürzburgGermany
  2. 2.Vascular Biology ProgrammHarvard Medical SchoolBostonUSA

Bibliographic information