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Early Nutrition and Lifestyle Factors

Effects on First Trimester Placenta

  • Asim K. Duttaroy
  • Sanjay Basak

Table of contents

  1. Front Matter
    Pages i-x
  2. Asim K. Duttaroy, Sanjay Basak
    Pages 13-21
  3. Asim K. Duttaroy, Sanjay Basak
    Pages 23-38
  4. Asim K. Duttaroy, Sanjay Basak
    Pages 39-50
  5. Asim K. Duttaroy, Sanjay Basak
    Pages 51-68
  6. Asim K. Duttaroy, Sanjay Basak
    Pages 91-100
  7. Asim K. Duttaroy, Sanjay Basak
    Pages 101-118
  8. Asim K. Duttaroy, Sanjay Basak
    Pages 119-128
  9. Asim K. Duttaroy, Sanjay Basak
    Pages 129-137
  10. Asim K. Duttaroy, Sanjay Basak
    Pages 139-149
  11. Asim K. Duttaroy, Sanjay Basak
    Pages 151-159

About this book

Introduction

This book highlights the impact of nutrients on early placentation processes and their relevance for fetal growth and pregnancy outcome.​ The role of maternal nutrition on fetal growth and development has been evidenced in many epidemiological studies that included infamous Dutch famine, Helsinki Birth cohort and others. Fetal programming hypothesis states that the nutritional and other environmental conditions under which an individual develops from pre-conception to birth has a major impact on the future health of the newborn child. The developmental environment of the fetus is primarily dependent on two major factors that are maternal nutritional state (excess/low/imbalance) and placental function. Placentation is characterized by the extensive remodeling of the maternal uterine vasculature producing low-resistance blood vessels that facilitate the exchange of nutrients and wastes between the mother and the fetus. Cellular and molecular mechanisms involved in human placental blood vessel formation, which are now well established, are discussed.

Keywords

Placentation Nutrition Intrauterine growth Trophoblast Angiogenic signaling Preeclampsia Blastocyst Early pregnancy Feto-placental unit Folic acid Vitamin supplementation Implantation Endometrium Placental epigenetics Lifestyle Factors

Authors and affiliations

  • Asim K. Duttaroy
    • 1
  • Sanjay Basak
    • 2
  1. 1.Dept of NutritionUniversity of Oslo Dept of NutritionOsloNorway
  2. 2.National Institute of NutritionIndian Council of Medical Research HyderabadIndia

Bibliographic information