Pituitary Adenylate Cyclase Activating Polypeptide — PACAP

  • Dora Reglodi
  • Andrea Tamas

Part of the Current Topics in Neurotoxicity book series (Current Topics Neurotoxicity, volume 11)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Evolutionary Aspects of PACAP

  3. Effects of PACAP in Neuronal Development

    1. Front Matter
      Pages 51-51
    2. Dan Lindholm, Johanna Mäkelä, Laura Korhonen
      Pages 53-63
    3. Jun Watanabe, Tamotsu Seki, Seiji Shioda
      Pages 65-82
  4. PACAP Receptors and Signalling

    1. Front Matter
      Pages 109-109
    2. Alain Fournier, Steve Bourgault, David Chatenet
      Pages 111-132
    3. David Chatenet, Alain Fournier, Steve Bourgault
      Pages 133-148
  5. Presence and Physiological Functions of PACAP in Diverse Systems

    1. Front Matter
      Pages 159-159
    2. Rodney L. Parsons, John D. Tompkins, Jean C. Hardwick, Laura A. Merriam, Beatrice M. Girard, Victor May
      Pages 205-225
    3. Andras Garami, Eszter Pakai, Zoltan Rumbus, Margit Solymar
      Pages 239-257
  6. Presence and Functions of PACAP in the Gastrointestinal and Urinary Tracts

    1. Front Matter
      Pages 259-259
    2. John P. Vu, Jihane N. Benhammou, Deepinder Goyal, Leon Luong, Suwan Oh, Patrizia Germano et al.
      Pages 261-269
    3. Gabriella Horvath, Anita Illes, Markus M. Heimesaat, Attila Bardosi, Sebastian Bardosi, Andrea Tamas et al.
      Pages 271-288
    4. Eric J. Gonzalez, Beatrice Girard, Karen M. Braas, Victor May, Margaret A. Vizzard
      Pages 313-334
  7. Functions of PACAP in the Skeletal System

    1. Front Matter
      Pages 335-335
    2. Tamas Juhasz, Andrea Tamas, Roza Zakany, Dora Reglodi
      Pages 337-353
    3. Balint Botz, Zsuzsanna Helyes
      Pages 355-372
  8. PACAP in the Regulation of the Reproductive System

    1. Front Matter
      Pages 375-375
    2. Haruhiko Kanasaki, Aki Oride, Mijiddorj Tselmeg, Unurjargal Sukhbaatar, Satoru Kyo
      Pages 375-387
    3. Gabriella Horvath, Jozsef Nemeth, Reka Brubel, Balazs Opper, Miklos Koppan, Andrea Tamas et al.
      Pages 389-403
    4. Rita Canipari, Virginia Di Paolo, Marzia Barberi, Sandra Cecconi
      Pages 405-420
  9. PACAP in Biological Barriers and Barrier-Forming Cells

  10. PACAP in Sensory Systems

    1. Front Matter
      Pages 481-481
    2. Tamas Atlasz, Alexandra Vaczy, Dora Werling, Peter Kiss, Andrea Tamas, Krisztina Kovacs et al.
      Pages 501-527
    3. Balazs D. Fulop, Dora Reglodi, Adrienn Nemeth, Andrea Tamas
      Pages 529-546
  11. Neuroprotective effects of PACAP

    1. Front Matter
      Pages 547-547
    2. Destiny-Love Manecka, Loubna Boukhzar, Anthony Falluel-Morel, Isabelle Lihrmann, Youssef Anouar
      Pages 549-561
    3. Karen M. Braas, Rodney L. Parsons, Margaret A. Vizzard, James A. Waschek, Victor May
      Pages 563-582
    4. Coralie Brifault, David Vaudry, Olivier Wurtz
      Pages 583-606
  12. PACAP in the Pathomechanism of Migraine and Pain

    1. Front Matter
      Pages 607-607
    2. Arsalan U. Syed, Masayo Koide, Victor May, George C. Wellman
      Pages 617-630
    3. Galen Missig, Rodney L. Parsons, Margaret A Vizzard, Sayamwong E. Hammack, Karen M. Braas, Victor May
      Pages 631-648
  13. Role of PACAP in Inflammatory Processes

    1. Front Matter
      Pages 649-649

About this book


The first comprehensive book to cover all aspects of the last 25 years of PACAP (pituitary adenylate cyclase activating polypeptide) research, this book contains contributions from virtually all the leading researchers in the field, and addresses some of the following topics: evolutionary aspects of PACAP, distribution and occurrence of PACAP and its receptors, hormonal effects of PACAP, intracellular signaling, effects on cellular proliferation and differentiation, protective effects of PACAP, behavioral effects of PACAP, developmental aspects of PACAP, other physiological effects of PACAP (cardiovascular, thermoregulatory), human studies, drug design, metabolism and transport. This compendium can serve as an important reference for researchers and students in PACAP research and can also be a thorough introduction for those in related fields.


PAC1 receptor PACAP VIP neuropeptide neuroprotection

Editors and affiliations

  • Dora Reglodi
    • 1
  • Andrea Tamas
    • 2
  1. 1.Department of Anatomy MTA-PTE “Lendulet” PACAP Research TeamUniversity of PecsPecsHungary
  2. 2.Department of Anatomy MTA-PTE “Lendulet” PACAP Research TeamUniversity of PecsPecsHungary

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-35133-9
  • Online ISBN 978-3-319-35135-3
  • Series Print ISSN 2363-9563
  • Series Online ISSN 2363-9571
  • Buy this book on publisher's site