Transcranial Direct Current Stimulation in Neuropsychiatric Disorders

Clinical Principles and Management

  • André Brunoni
  • Michael Nitsche
  • Colleen Loo

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Introduction and Mechanisms of Action

    1. Front Matter
      Pages 1-1
    2. Stefano Zago, Alberto Priori, Roberta Ferrucci, Lorenzo Lorusso
      Pages 3-19
    3. Andrea Antal, Ivan Alekseichuk, Walter Paulus
      Pages 21-28
    4. Min-Fang Kuo, Rafael Polanía, Michael Nitsche
      Pages 29-46
    5. Dennis Q. Truong, Devin Adair, Marom Bikson
      Pages 47-66
    6. Doris Ling, Asif Rahman, Mark Jackson, Marom Bikson
      Pages 67-83
    7. Natasha Radhu, Daniel M. Blumberger, Zafiris J. Daskalakis
      Pages 85-102
    8. Siobhán Harty, Anna-Katharine Brem, Roi Cohen Kadosh
      Pages 103-141
    9. Paulo Sérgio Boggio, Gabriel Gaudencio Rêgo, Lucas Murrins Marques, Thiago Leiros Costa
      Pages 143-152
    10. Nadia Bolognini, Carlo Miniussi
      Pages 153-168
    11. Ainslie Johnstone, Emily Hinson, Charlotte J. Stagg
      Pages 169-195
    12. Flavio Fröhlich, Sankaraleengam Alagapan, Michael R. Boyle, Franz Hamilton, Guoshi Li, Caroline Lustenberger et al.
      Pages 197-222
    13. Roberta Ferrucci, Tommaso Bocci, Alberto Priori
      Pages 223-229
  3. Applications of tDCS in Neuropsychiatric Disorders

    1. Front Matter
      Pages 231-231
    2. André Brunoni, Colleen Loo
      Pages 233-244
    3. Marine Mondino, Clara Fonteneau, Jérôme Brunelin
      Pages 245-264
    4. Giordano D’Urso, Teresa Sassi, Andrea de Bartolomeis, Antonio Mantovani
      Pages 265-271
    5. Tarek K. Rajji
      Pages 273-280
    6. Sara Labbe, Shirley Fecteau
      Pages 281-291
    7. Sameer C. Dhamne, Yan Sun, Alexander Rotenberg
      Pages 293-298
    8. Alexandre F. M. DaSilva, Marcos Fabio DosSantos
      Pages 299-314
    9. Nam-Jong Paik, Won-Seok Kim
      Pages 315-328
    10. Thibaut Aurore, Di Perri Carol, Laureys Steven
      Pages 329-339
  4. The Clinical Use of tDCS

    1. Front Matter
      Pages 341-341
    2. André Brunoni, Colleen Loo, Michael Nitsche
      Pages 343-350
    3. Angelo Alonzo, Leigh Charvet
      Pages 351-361
    4. Rachel P. Wurzman, Roy H. Hamilton
      Pages 363-382
    5. Alejandra Vasquez, Felipe Fregni
      Pages 383-392
    6. Adam J. Woods, Donel M. Martin
      Pages 393-404
  5. Back Matter
    Pages 405-414

About this book


The aim of this book is to provide a comprehensive review of the use of Transcranial Direct Current Stimulation (tDCS) in different psychiatric conditions. Here we review tDCS clinical studies employing different types of design (from single-session tDCS studies to randomized clinical trials) as well as studies evaluating the impact of tDCS in neurophysiological, behavioral and brain imaging outcomes.

Although the understanding about physiological foundations and effectiveness of clinical therapies of psychiatric diseases has been considerably increased during the last decades, our knowledge is still limited, and consequently psychiatric diseases are still a major burden to the individual patient and society. Recently, interest in pathological alterations of neuroplasticity in psychiatric diseases as a critical condition for development, and amelioration of clinical symptoms increased, caused by the fact that new tools, such as functional imaging, and brain stimulation techniques do allow to monitor, and modulate these phenomena in humans. Especially non-invasive brain stimulation techniques evolved as an attractive potential new therapeutic tool. The interest in non-invasive brain stimulation has grown exponentially in the past 25 years, with the development of non-pharmacological, neuromodulatory techniques such as tDCS and repetitive transcranial magnetic stimulation (rTMS). TDCS, although even newer than rTMS, has attracted considerable attention in both basic and clinical research scenarios. In the context of clinical research, tDCS is being increasingly investigated as a novel treatment tool for several psychiatric disorders, such as major depression, schizophrenia and neurocognitive and substance abuse disorders.

Transcranial Direct Current Stimulation in Neuropsychiatric Disorders – Clinical Principles and Management intends to serve as a practical guide on the field, attracting the interest of psychiatrists, neurologists and neuroscientists with little or no experience with tDCS, as well as those with a background on tDCS who want to increase their knowledge in any particular psychiatric condition.


Major depressive disorder Neuropsychiatry Psychiatric disorders Psychopharmacology Somatic therapies Transcranial direct current stimulation

Editors and affiliations

  • André Brunoni
    • 1
  • Michael Nitsche
    • 2
  • Colleen Loo
    • 3
  1. 1.Interdisciplinary Center for Applied Neuromodulation Department and Institute of Psychiatry Laboratory of Neurosciences (LIM-27)University Hospital and Service of Interdisciplinary Neuromodulation University of São PauloSão PauloBrazil
  2. 2.Department of Psychology and NeurosciencesLeibniz Research Center for Working Environments and Human FactorsDortmundGermany
  3. 3.School of Psychiatry Black Dog Institute & St George HospitalUniversity of New South WalesSydneyAustralia

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-33965-8
  • Online ISBN 978-3-319-33967-2
  • Buy this book on publisher's site