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Autophagy at the Cell, Tissue and Organismal Level

  • Eleftherios Karanasios
  • Nicholas T. Ktistakis

Part of the SpringerBriefs in Cell Biology book series (SBCB)

Table of contents

  1. Front Matter
    Pages i-vi
  2. Eleftherios Karanasios, Nicholas T. Ktistakis
    Pages 1-5
  3. Eleftherios Karanasios, Nicholas T. Ktistakis
    Pages 7-15
  4. Eleftherios Karanasios, Nicholas T. Ktistakis
    Pages 17-33
  5. Eleftherios Karanasios, Nicholas T. Ktistakis
    Pages 35-50
  6. Eleftherios Karanasios, Nicholas T. Ktistakis
    Pages 51-80
  7. Eleftherios Karanasios, Nicholas T. Ktistakis
    Pages 81-103

About this book

Introduction

This book provides an expert summary of autophagy, a relatively new but rapidly expanding field of biomedical science with important implications in health and disease. After a historical review ranging up to the identification of autophagy genes in mammals, the authors discuss the signaling pathways that regulate autophagy, the mechanism of autophagosome formation and the physiological roles of autophagy in development, ageing, neurodegeneration, immune function and cell differentiation. A comprehensive list of useful antibodies for studying autophagy compiled as a community effort is included at the end. The book is intended for newcomers to the field, as well as more experienced researchers looking for a condensed but comprehensive introduction to the physiological function and regulation of the autophagic pathway in mammalian organisms.

Keywords

Autophagosome formation Basic mechanisms of autophagy Immunity and autophagy Physiological roles of autophagy Signalling of autophagy processes TORC1 signalling

Authors and affiliations

  • Eleftherios Karanasios
    • 1
  • Nicholas T. Ktistakis
    • 2
  1. 1.Babraham InstituteBabraham, CambridgeUnited Kingdom
  2. 2.Babraham InstituteBabraham, CambridgeUnited Kingdom

Bibliographic information