Non-Neuronal Mechanisms of Brain Damage and Repair After Stroke

  • Jun Chen
  • John H. Zhang
  • Xiaoming Hu

Part of the Springer Series in Translational Stroke Research book series (SSTSR)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Microvascular Integrity in Stroke

    1. Front Matter
      Pages 1-1
    2. Anuska V. Andjelkovic, Richard F. Keep
      Pages 3-23
    3. Turgay Dalkara, Luis Alarcon-Martinez, Muge Yemisci
      Pages 25-43
    4. Zinaida S. Vexler
      Pages 81-92
    5. Ke-Jie Yin, Xinxin Yang
      Pages 93-108
  3. Glial Cells in Stroke

    1. Front Matter
      Pages 109-109
    2. Shinghua Ding
      Pages 111-131
    3. Hong Shi, Mingyue Xu, Yejie Shi, Yanqin Gao, Jun Chen, Xiaoming Hu
      Pages 133-150
    4. Akihiro Shindo, Takakuni Maki, Kanako Itoh, Nobukazu Miyamoto, Naohiro Egawa, Anna C. Liang et al.
      Pages 151-170
  4. Peripheral Immune Cells in Stroke

    1. Front Matter
      Pages 171-171
    2. Josef Anrather
      Pages 173-188
    3. Arthur Liesz
      Pages 201-215
    4. Uma Maheswari Selvaraj, Katie Poinsatte, Ann M. Stowe
      Pages 217-254
    5. Perttu J. Lindsberg, Olli S. Mattila, Daniel Strbian
      Pages 255-272
    6. Glen C. Jickling, Frank R. Sharp
      Pages 273-301
    7. Christopher C. Leonardo, Keith R. Pennypacker
      Pages 303-323
  5. White Matter Injury and Repair in Stroke

    1. Front Matter
      Pages 325-325
    2. Sylvain Brunet, Chinthasagar Bastian, Selva Baltan
      Pages 327-343
  6. Emerging Therapies to Target Non-neuronal Mechanisms After Stroke

    1. Front Matter
      Pages 345-345
    2. Sherrefa R. Burchell, Wing-Mann Ho, Jiping Tang, John H. Zhang
      Pages 347-375
    3. Hung Nguyen, Naoki Tajiri, Cesar V. Borlongan
      Pages 399-408

About this book


This book provides a comprehensive overview of the latest research in the role of non-neuronal cells - astrocytes, oligodendrocytes, endothelial cells, pericytes, microglia, and other immune cells in ischemic brain injury and long-term recovery. In these cases, neurodegeneration and brain repair are controlled in a sophisticated system, incorporating interactions between different cell types and cellular systems. Also explored are the therapeutic strategies that target non-neuronal responses after stroke and their translational potentials.


blood brain barrier brain repair neuroinflammation therapies white matter

Editors and affiliations

  • Jun Chen
    • 1
  • John H. Zhang
    • 2
  • Xiaoming Hu
    • 3
  1. 1.Department of NeurologyUniversity of PittsburghPittsburghUSA
  2. 2.Pittsburgh Institute of Brain Disorders and RecoveryUniversity of PittsburghPittsburghUSA
  3. 3.Department of AnesthesiologyLoma Linda University School of MedicineLoma LindaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-32335-0
  • Online ISBN 978-3-319-32337-4
  • Series Print ISSN 2363-958X
  • Series Online ISSN 2363-9598
  • Buy this book on publisher's site