Safety of Biologics Therapy

Monoclonal Antibodies, Cytokines, Fusion Proteins, Hormones, Enzymes, Coagulation Proteins, Vaccines, Botulinum Toxins

  • Brian A.¬†Baldo

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Brian A. Baldo
    Pages 29-56
  3. Brian A. Baldo
    Pages 217-261
  4. Brian A. Baldo
    Pages 263-307
  5. Brian A. Baldo
    Pages 309-400
  6. Brian A. Baldo
    Pages 401-417
  7. Brian A. Baldo
    Pages 419-477
  8. Brian A. Baldo
    Pages 479-513
  9. Brian A. Baldo
    Pages 515-557
  10. Brian A. Baldo
    Pages 559-585
  11. Brian A. Baldo
    Pages 587-596
  12. Back Matter
    Pages 597-610

About this book


This long overdue title provides a comprehensive, up-to-date, state-of-the art review of approved biologic therapies, with coverage of mechanisms of action, Indications for therapy, immunogenicity and a detailed examination of adverse effects and safety of the many and diverse therapeutic agents presented in a total of 13 chapters.  It is predicted that by 2016, biologics will make up half of the world's 20 top-selling drugs and by 2018, biologic medicine sales will account for almost half of the world's 100 biggest selling drugs. Recombinant proteins dominate the growing list of the more than 200 approved biotherapeutic agents with targeted antibodies, fusion proteins and receptors; cytokines; hormones; enzymes; proteins involved in blood-clotting, homeostasis and thrombosis; vaccines; botulinum neurotoxins; and, more recently, biosimilar preparations, comprising the majority of approved biologics. Written with clinicians, other health care professionals, and researchers in mind, Safety of Biologics Therapy examines, in a single volume, the full range of issues surrounding the safety of approved biologic therapies. A good understanding of the risks and safety issues of modern biologics therapy is increasingly being demanded of all those connected with their development, handling, prescribing, administration and subsequent patient management. In addition to being of great value to clinicians in all branches of medicine, and to nurses, pharmacists and researchers, this book will prove invaluable for students taking undergraduate and graduate courses in the above disciplines and in the biomedical sciences.


antibodies insulin mABS theraputic agents chimeric fusion proteins cytokines hormones enzymes

Authors and affiliations

  • Brian A.¬†Baldo
    • 1
  1. 1.Royal North Shore Hospital of Sydney HeadMolecular Immunology Unit Kolling Institute of Medical Research and University of SydneySydneyAustralia

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-30470-0
  • Online ISBN 978-3-319-30472-4
  • Buy this book on publisher's site