Book 2016

Vascular Ion Channels in Physiology and Disease

Editors:

ISBN: 978-3-319-29633-3 (Print) 978-3-319-29635-7 (Online)

Table of contents (18 chapters)

  1. Front Matter

    Pages i-xvii

  2. Ion Channel Regulation of Vascular Tone and Blood Flow. Changes with Hypertension: Endothelial Cells

    1. Front Matter

      Pages 1-1

    2. No Access

      Chapter

      Pages 3-36

      Endothelial Cell Ion Channel Expression and Function in Arterioles and Resistance Arteries

    3. No Access

      Chapter

      Pages 37-62

      Contribution and Regulation of Calcium Channels in Endothelial Cells

    4. No Access

      Chapter

      Pages 63-78

      Mitochondrial Depolarization in Endothelial and Other Vascular Cells and Their Role in the Regulation of Cerebral Vascular Tone

    5. No Access

      Chapter

      Pages 79-99

      Ion Channels in Control of Blood Flow: Electrical Conduction Along Endothelium of Resistance Arteries

    6. No Access

      Chapter

      Pages 101-127

      Ca2+/Calmodulin-Gated Small- and Intermediate-Conductance KCa Channels in Cardiovascular Regulation: Targets for Novel Pharmacological Treatments

  3. Ion Channel Regulation of Vascular Tone and Blood Flow. Changes with Hypertension: Smooth Muscle Cell

    1. Front Matter

      Pages 129-129

    2. No Access

      Chapter

      Pages 131-152

      Regional Variation in Arterial Myogenic Responsiveness: Links to Potassium Channel Diversity/Function

    3. No Access

      Chapter

      Pages 153-168

      Ion Channel Trafficking and Control of Arterial Contractility

    4. No Access

      Chapter

      Pages 169-190

      Abnormalities of Vascular Ion Channels During Hypertension

    5. No Access

      Chapter

      Pages 191-214

      Kv7 Potassium Channels as Therapeutic Targets in Cerebral Vasospasm

    6. No Access

      Chapter

      Pages 215-229

      Lysosomal Transient Receptor Potential Mucolipin (TRPML) Channels in Vascular Regulation and Diseases

  4. Ion Channels in the Regulation of Cell Proliferation, Remodeling, Hypertrophy and Angiogenesis

    1. Front Matter

      Pages 231-231

    2. No Access

      Chapter

      Pages 233-253

      Calcium Mobilization via Intracellular Ion Channels, Store Organization and Mitochondria in Smooth Muscle

    3. No Access

      Chapter

      Pages 255-273

      Role of Mechanosensitive TRP Channels in Abnormal Vasculature of Tumors

    4. No Access

      Chapter

      Pages 275-294

      TRPC and Orai Channels in Store-Operated Calcium Entry and Vascular Remodelling

    5. No Access

      Chapter

      Pages 295-324

      Smooth Muscle Cell Ion Channels in Pulmonary Arterial Hypertension: Pathogenic Role in Pulmonary Vasoconstriction and Vascular Remodeling

  5. Ion Channel Regulation by Lipids and Channel Modifications in Metabolic Disease

    1. Front Matter

      Pages 325-325

    2. No Access

      Chapter

      Pages 327-347

      Physiological Roles and Cholesterol Sensitivity of Endothelial Inwardly-Rectifying K+ Channels: Specific Cholesterol-Protein Interactions Through Non Annular Binding Sites

    3. No Access

      Chapter

      Pages 349-380

      Membrane Lipids and Modulation of Vascular Smooth Muscle Ion Channels

    4. No Access

      Chapter

      Pages 381-396

      Transient Receptor Potential Channels in Metabolic Syndrome-Induced Coronary Artery Disease

    5. No Access

      Chapter

      Pages 397-419

      Mitochondrial Ion Channels in Metabolic Disease

  6. Back Matter

    Pages 421-431