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Targeting the IL-17 Pathway in Inflammatory Disorders

  • Cong-Qiu Chu

Table of contents

About this book

Introduction

This book provides an overview of the discovery and structure of IL-17, including its pathogenesis and role in chronic inflammation and autoimmunity. To capture the latest developments and product approvals the book also discusses the therapeutic advances and looks at emerging therapies targeting the IL-17 pathway. IL-17 is a pro-inflammatory cytokine that has a key role in inflammation, autoimmunity, and host defense in a number of inflammatory disorders such as rheumatoid arthritis, psoriatic arthritis and psoriasis, ankylosing spondylitis, multiple sclerosis, and inflammatory bowel disease. The discovery of the IL-17-Th17 pathway has seen exciting development in the field of immunology and inflammation research, which has led to a number of recent regulatory approvals.

Keywords

Rheumatology Dermatology IL-17 Inflammatory disorders Chronic inflammation Autoimmunity Rheumatoid arthritis Psoriatic arthritis Psoriasis Ankylosing spondylitis

Authors and affiliations

  • Cong-Qiu Chu
    • 1
  1. 1.VA Portland Health Care SystemOregon Health & Science UniversityPortlandUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-28040-0
  • Copyright Information Springer International Publishing Switzerland 2017
  • Publisher Name Adis, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-28039-4
  • Online ISBN 978-3-319-28040-0
  • Buy this book on publisher's site