The Hsp60 Chaperonin

  • Peter┬áBross

Part of the SpringerBriefs in Molecular Science book series (BRIEFSMOLECULAR)

Also part of the Protein Folding and Structure book sub series (BRIEFSPROTEIN)

About this book


In this unique overview of the Hsp60 chaperonin, Peter Bross addresses molecular biologists, medical research scientists and individuals interested in molecular or general biology. First, Bross discusses the basics of the Hsp60 chaperonin in terms of its structure and the molecular mechanisms determining its function. Second, the author highlights the multiple roles of Hsp60 for cellular systems and regulatory pathways, especially in connection with neurodegenerative diseases caused by Hsp60 deficiency. Finally, the author highlights controversial observations suggesting additional, non-standard functions of Hsp60 in and outside mitochondria as well as possible gaps in our understanding of the chaperonin. This volume serves as a snapshot suitable for experienced researcher working in fields related to molecular chaperones yet still accessible to researchers entering the field.


Chaperonin Hsp60 Hsp60 Function in Mitochondria Molecular Chaperone Neurodegeneration Protein Assembly Protein Folding Protein Quality Control

Authors and affiliations

  • Peter┬áBross
    • 1
  1. 1.Department of Clinical Medicine,Aarhus University and Aarhus, UniversityAarhus NDenmark

Bibliographic information

  • DOI
  • Copyright Information The Author(s) 2015
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-26086-0
  • Online ISBN 978-3-319-26088-4
  • Series Print ISSN 2191-5407
  • Series Online ISSN 2191-5415
  • Buy this book on publisher's site